SPCS3

Gene Symbol SPCS3
Entrez Gene 60559
Alt Symbol PRO3567, SPC22/23, SPC3, YLR066W
Species Human
Gene Type protein-coding
Description signal peptidase complex subunit 3 homolog (S. cerevisiae)
Other Description SPase 22 kDa subunit|SPase 22/23 kDa subunit|microsomal signal peptidase 22/23 kDa subunit|microsomal signal peptidase 23 kDa subunit|signal peptidase complex subunit 3
Swissprots P61009
Accessions CAH05566 EAX04718 EAX04719 P61009 AK026302 BAB15437 AK092634 AL136660 CAB66595 AY359044 AAQ89403 BC043490 BC047290 AAH47290 BC053883 DB285025 EU831652 ACE87252 EU831735 ACE86569 HQ448610 ADQ33088 NM_021928 NP_068747
Function Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
Subcellular Location Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Top Pathways Protein export

SPCS3 (E-14) - sc-138642 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
SPCS3 (E-14): sc-138642. Western blot analysis of SPCS3 expression in non-transfected: sc-117752 (A) and human SPCS3 transfected: sc-116023 (B) 293T whole cell lysates.

SPCS3 (G-7) - sc-377334 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SPCS3 (G-7): sc-377334. Western blot analysis of SPCS3 expression in non-transfected: sc-117752 (A) and human SPCS3 transfected: sc-116023 (B) 293T whole cell lysates.

Anti-SPCS3 antibody - ab91222 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SPCS3 antibody (ab91222) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

Anti-SPCS3 Antibody (aa51-100) - LS-C169843 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SPCS3 Antibody (aa152-180) - LS-C98411 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SPCS3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

SPCS3 Antibody - NBP2-30420 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SPCS3 Antibody [NBP2-30420] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

SPCS3 Antibody - H00060559-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SPCS3 Antibody [H00060559-A01] - SPCS3 polyclonal antibody (A01), Lot # 060524JCS1 Western Blot analysis of SPCS3 expression in Hela NE ( Cat # L013V3 ).

Anti-SPCS3 antibody produced in rabbit - HPA053180 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SPCS3: <B>Cat. No. HPA053180</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

ANTI-SPCS3 (C-TERM) antibody produced in rabbit - SAB1302993 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>SPCS3 (C-term): <B>Cat. No. SAB1302993</B>: SPCS3 in Human hepatocarcinoma tissue with SPCS3 antibody (C-term) at 5 μg/mL.

Anti-SPCS3 (51-65) antibody produced in rabbit - SAB1102420 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human SPCS3 was separated on SDS-PAGE, blotted with Anti-SPCS3 (51-65) (<B>Cat. No. SAB1102420</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:2,000

SPCS3 Antibody - middle region (ARP66955_P050) - ARP66955_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SPCS3-Antibody-C-term - AP6676b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of SPCS3 antibody (C-term) (Cat. #AP6676b) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.

SPCS3 Antibody - C-terminal region (OAAB03724) - OAAB03724 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SPCS3 Antibody - abx032927 from Abbexa

Host Rabbit
Clonality Polyclonal

SPCS3 / SPC22 (C-term) antibody - AP17761PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of SPCS3 antibody (C-term) (AP17761PU-N) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.

SPCS3 / SPC22 antibody - H00060559-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
SPCS3 polyclonal antibody (A01), Lot # 060524JCS1 Western Blot analysis of SPCS3 expression in Hela NE ( Cat # L013V3 ).

Rabbit Anti-SPCS3 (C-term) - 102-16880 from RayBiotech

Host Rabbit
Western blot analysis of SPCS3 antibody (C-term) (Cat# 102-16880) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.

SPCS3 antibody (C-term) - STJ50120 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB20252

SPCS3 antibody - 17640-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

SPCS3, Polyclonal Antibody - MBS630419 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPCS3 (aa 32-141) polyclonal antibody - DPAB-DC2710 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-SPCS3 (aa 51-100) polyclonal antibody - DPABH-02028 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-SPCS3 monoclonal antibody - DCABH-16952 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

SPCS3, Polyclonal Antibody - MBS9206024 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

SPCS3 Antibody - abx122924 from Abbexa

Host Rabbit
Clonality Polyclonal
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