GPM6A

Gene Symbol	GPM6A
Entrez Gene	2823
Alt Symbol	GPM6, M6A
Species	Human
Gene Type	protein-coding
Description	glycoprotein M6A
Other Description	neuronal membrane glycoprotein M6-a
Swissprots	Q92602 B7Z642 E9PHI5 P51674
Accessions	EAX04724 EAX04725 P51674 AI609188 AK226176 AK299788 BAH13128 AX772804 CAE06251 BC010461 BC022508 AAH22508 BC022528 AAH22528 BC032904 BC037853 AAH37853 BC044612 AAH44612 BC053954 BI544825 BI546539 BI596896 BI670059 D49958 BAA08712 DA190376 DA196860 DA507772 DA528125 DA621566 DA915764 DC353381 DQ892372 ABM83298 DQ895581 ABM86507 H16369 U45956 AAB16889 XM_006714183 XP_006714246 XM_011531877 XP_011530179 NM_001261447 NP_001248376 NM_001261448 NP_001248377 NM_005277 NP_005268 NM_201591 NP_963885 NM_201592 NP_963886 NR_048571
Function	Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. {ECO:0000269|PubMed:19298174}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, axon {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons (By similarity). {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Neuronal membrane glycoprotein M6-a peptide - ab103571 from Abcam Category Peptide

GPM6A / Glycoprotein M6A Antibody Blocking Peptide - LS-E1974 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPM6A / Glycoprotein M6A Antibody Blocking Peptide - LS-E23687 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPM6A / Glycoprotein M6A Antibody Blocking Peptide - LS-E23686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPM6A / Glycoprotein M6A Antibody Blocking Peptide - LS-E27549 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPM6A / Glycoprotein M6A Antibody Blocking Peptide - LS-E10076 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPM6A-Antibody-C-term-Blocking-peptide - BP12829b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPM6A-Antibody-C-term-Blocking-Peptide - BP9341b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Neuronal Membrane Glycoprotein M6-A Peptide - AC21-2371-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GPM6A Peptide - 42-708P from ProSci Category Peptide Species Human, Mouse, Rat

GPM6A fusion protein - ag6915 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human GPM6A, GST-tagged - GPM6A-13428H from Creative Biomart Category Protein Source E.coli Species Human

GPM6A (transcript variant 2) - TP305371 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GPM6A (transcript variant 1) - TP305432 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GPM6A (transcript variant 3) - TP313529 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GPM6A, Peptide - MBS427621 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

GPM6A Recombinant Protein Antigen - NBP1-81799PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GPM6A Peptide, Human - M34GP06500H from Creative Peptides Category Peptide Source Synthetic. Species Human

GPM6A Antibody - SH-A12451 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

Neuronal membrane glycoprotein M6-a (GPM6A), Recombinant Protein - MBS7016043 from MyBioSource Category Protein Prices $1,090.00, $2,075.00, $3,285.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Neuronal membrane glycoprotein M6-a (GPM6A), Recombinant Protein - MBS7016045 from MyBioSource Category Protein Prices $1,090.00, $2,075.00, $3,285.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Orangutan

Neuronal membrane glycoprotein M6-a (GPM6A), Recombinant Protein - MBS950912 from MyBioSource Category Protein Prices $875.00, $875.00, $1,100.00, $1,100.00, $1,220.00, $1,220.00, $1,680.00, $1,680.00, $1,715.00, $2,415.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

GPM6A Immunizing peptide - orb59967 from Biorbyt Category Peptide

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