Gene Symbol | PROCR |
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Entrez Gene | 10544 |
Alt Symbol | CCCA, CCD41, EPCR |
Species | Human |
Gene Type | protein-coding |
Description | protein C receptor, endothelial |
Other Description | APC receptor|CD201 antigen|activated protein C receptor|cell cycle, centrosome-associated protein|centrocyclin|endothelial protein C receptor |
Swissprots | Q9ULX1 B2RC04 Q96CB3 Q9UNN8 Q6IB56 Q14218 |
Accessions | AAD43967 AAK53045 BAA77249 EAW76223 EAW76224 Q9UNN8 AK314887 BAG37401 BC014451 AAH14451 BG423815 BM808358 BQ939781 CR456948 CAG33229 DQ892834 ABM83760 DQ896081 ABM87080 HY110044 L35545 AAA63647 X89079 CAA61450 XM_011528496 XP_011526798 NM_006404 NP_006395 |
Function | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. |
EPCR CRISPR/Cas9 KO Plasmid (h) - sc-402158 from Santa Cruz Biotechnology
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EPCR HDR Plasmid (h) - sc-402158-HDR from Santa Cruz Biotechnology
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EPCR Double Nickase Plasmid (h) - sc-402158-NIC from Santa Cruz Biotechnology
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EPCR Double Nickase Plasmid (h2) - sc-402158-NIC-2 from Santa Cruz Biotechnology
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EPCR CRISPR Activation Plasmid (h) - sc-402158-ACT from Santa Cruz Biotechnology
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EPCR CRISPR Activation Plasmid (h2) - sc-402158-ACT-2 from Santa Cruz Biotechnology
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EPCR Lentiviral Activation Particles (h) - sc-402158-LAC from Santa Cruz Biotechnology
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EPCR Lentiviral Activation Particles (h2) - sc-402158-LAC-2 from Santa Cruz Biotechnology
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EPCR siRNA (h) - sc-39932 from Santa Cruz Biotechnology
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EPCR shRNA Plasmid (h) - sc-39932-SH from Santa Cruz Biotechnology
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EPCR shRNA (h) Lentiviral Particles - sc-39932-V from Santa Cruz Biotechnology
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EPCR RNAi - H00010544-R02 from Novus Biologicals
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MISSION® esiRNA - EHU034481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17453 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17453 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04203 from Sigma-Aldrich
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PROCR siRNA (Human) - CRH7168 from Cohesion Biosciences
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shRNA set against Human PROCR (NM_006404.3) - SHH383460 from Creative biogene
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shRNA set against Human PROCR(NM_006404.3) - SHR141666 from Creative biogene
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PROCR shRNA Plasmid (Human) - CHH7168 from Cohesion Biosciences
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PROCR miRNA 3'UTR clone - MiUTR1H-08305 from Creative biogene
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