Gene Symbol |
CPSF1
|
Entrez Gene |
282703
|
Alt Symbol |
-
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
cleavage and polyadenylation specific factor 1, 160kDa
|
Other Description |
CPSF 160 kDa subunit|cleavage and polyadenylation specificity factor 1|cleavage and polyadenylation specificity factor 160 kDa subunit|cleavage and polyadenylation specificity factor subunit 1
|
Swissprots |
Q10569
|
Accessions |
CAD58786 CAD58787 DAA22845 Q10569 X83097 CAA58152 XM_005215130 XP_005215187 XM_010811817 XP_010810119 XM_010811818 XP_010810120 XM_010811819 XP_010810121 NM_174720 NP_777145
|
Function |
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus, nucleoplasm.
|
Top Pathways |
mRNA surveillance pathway
|