| Gene Symbol | ABAT |
|---|---|
| Entrez Gene | 18 |
| Alt Symbol | GABA-AT, GABAT, NPD009 |
| Species | Human |
| Gene Type | protein-coding |
| Description | 4-aminobutyrate aminotransferase |
| Other Description | (S)-3-amino-2-methylpropionate transaminase|4-aminobutyrate aminotransferase, mitochondrial|4-aminobutyrate transaminase|GABA aminotransferase|GABA transaminase|GABA transferase|gamma-amino-N-butyrate transaminase |
| Swissprots | Q99800 Q8N5W2 P80404 A8K386 Q96BG2 Q16260 |
| Accessions | EAW85207 EAW85208 EAW85209 P80404 AA806200 AF237813 AAG09758 AK054834 AK096146 AK290501 BAF83190 AK293983 BAH11640 AK310771 AL137454 BC008990 BC013965 BC015628 AAH15628 BC031413 AAH31413 BC075851 BG749438 BG818982 BI459888 BI602086 BX537362 DA228305 DA300126 DA531116 DB443567 DB479117 DC335224 DQ893069 ABM83995 DQ896323 ABM87322 KJ534758 AHW56398 KJ535005 AHW56644 L32961 AAA74449 S75578 AAD14176 U80226 AAB38510 XM_011522400 XP_011520702 XM_011522401 XP_011520703 NM_000663 NP_000654 NM_001127448 NP_001120920 NM_020686 NP_065737 |
| Function | Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. |
| Subcellular Location | Mitochondrion matrix. |
| Tissue Specificity | Liver > pancreas > brain > kidney > heart > placenta. |
| Top Pathways | GABAergic synapse, Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Butanoate metabolism |