| Gene Symbol |
CHRNA7
|
| Entrez Gene |
282178
|
| Alt Symbol |
-
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, alpha 7
|
| Other Description |
alpha 7 nicotinic acetylcholine receptor|cholinergic receptor, nicotinic, alpha polypeptide 7|neuronal acetylcholine receptor subunit alpha-7
|
| Swissprots |
P54131
|
| Accessions |
DAA17501 P54131 BC149340 AAI49341 X93604 CAA63802 NM_174515 NP_776940
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
At least in chromaffin cells.
|
| Top Pathways |
Calcium signaling pathway, Chemical carcinogenesis, Nicotine addiction, Neuroactive ligand-receptor interaction
|