Gene Symbol | DCAF7 |
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Entrez Gene | 10238 |
Alt Symbol | AN11, HAN11, SWAN-1, WDR68 |
Species | Human |
Gene Type | protein-coding |
Description | DDB1 and CUL4 associated factor 7 |
Other Description | DDB1- and CUL4-associated factor 7|WD repeat-containing protein 68|WD repeat-containing protein An11 homolog|human anthocyanin|seven-WD-repeat protein of the AN11 family-1 |
Swissprots | D3DU14 P61962 B4E039 |
Accessions | EAW94305 EAW94306 P61962 AA206721 AA634196 AI580937 AK022145 AK025925 AK026008 AK130672 AK294925 BAG58007 AK303212 BAG64301 AL832440 BC001264 AAH01264 BC024682 BC027489 BE889428 BF058090 BF507629 BG684075 BG819062 BM272287 BM559804 BM673647 BQ221019 BQ435051 BX648608 CB162675 CD245570 DA230140 DQ891233 ABM82159 DQ894417 ABM85343 HY023965 U94747 AAC18913 NM_005828 NP_005819 NR_073585 NM_001003725 |
Function | Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000250, ECO:0000269|PubMed:16887337, ECO:0000269|PubMed:16949367}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm. |
Human WDR68 protein fragment - ab111624 from Abcam
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DCAF7 / WDR68 Antibody Blocking Peptide - LS-E4936 from LifeSpan Bioscience
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DCAF7 / WDR68 Antibody Blocking Peptide - LS-E18710 from LifeSpan Bioscience
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WDR68 Recombinant Protein - H00010238-P01 from Novus Biologicals
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Recombinant Human WDR68 Protein - NBP1-72421 from Novus Biologicals
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WDR68-Antibody-C-term-Blocking-Peptide - BP17326b from Abgent, a WuXi AppTec company
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Human DCAF7 protein - orb168195 from Biorbyt
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Human DCAF7 protein - orb244630 from Biorbyt
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Dcaf7 Blocking Peptide - 33R-8588 from Fitzgerald
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DCAF7 protein (His tag) - 80R-1937 from Fitzgerald
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DCAF7 (19-295, His-tag) - AR39119PU-L from Acris Antibodies
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DCAF7 (19-295, His-tag) - AR39119PU-N from Acris Antibodies
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DCAF7 - H00010238-P01-10 from Acris Antibodies
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DCAF7 - H00010238-P01-25 from Acris Antibodies
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DDB1 and CUL4 Associated Factor 7, Human Recombinant - 228-13348-1 from RayBiotech
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Recombinant Human DDB1 and CUL4 Associated Factor 7 - 228-13348-2 from RayBiotech
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Recombinant Human DDB1 and CUL4 Associated Factor 7 - 228-13348-3 from RayBiotech
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DCAF7, 19-295aa, Human, His tag, E.coli - 01-P1177 from ARP American Research Products
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WDR68 fusion protein - ag2295 from Proteintech Group
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DCAF7 Human - PRPS-916 from NeoScientific
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Recombinant Human DDB1 and CUL4 Associated Factor 7 Protein - BP002895-PRO-909 from Syd Labs
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DCAF7, 19-295aa, Recombinant Protein - GWB-P0861C from Genway Biotech
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Recombinant Human DCAF7, His-tagged - DCAF7-30698TH from Creative Biomart
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Recombinant Human DDB1 And CUL4 Associated Factor 7, T7-tagged - DCAF7-3012H from Creative Biomart
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Recombinant Human DCAF7, His-tagged - DCAF7-3624H from Creative Biomart
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