Gene Symbol | CLCNKA |
---|---|
Entrez Gene | 1187 |
Alt Symbol | CLCK1, ClC-K1, hClC-Ka |
Species | Human |
Gene Type | protein-coding |
Description | chloride channel, voltage-sensitive Ka |
Other Description | chloride channel Ka|chloride channel protein ClC-Ka|chloride channel, kidney, A |
Swissprots | Q86VT1 Q7Z6D1 Q5T5Q4 E7EPH6 P51800 B4DPD3 Q5T5P8 |
Accessions | AAB65148 EAW51763 P51800 AI821546 AK225550 AK290814 BAF83503 AK293476 BAG56967 AK293586 BAH11540 AK298285 BAG60545 BC035373 BC048282 AAH48282 BC053869 AAH53869 Z30643 CAA83120 NM_001042704 NP_001036169 NM_001257139 NP_001244068 NM_004070 NP_004061 |
Function | Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed predominantly in the kidney. All nephron segments expressing BSND also express CLCNK proteins. {ECO:0000269|PubMed:11734858}. |
CLC-KA CRISPR/Cas9 KO Plasmid (h) - sc-404050 from Santa Cruz Biotechnology
|
||||||||
CLC-KA HDR Plasmid (h) - sc-404050-HDR from Santa Cruz Biotechnology
|
||||||||
CLC-KA Double Nickase Plasmid (h) - sc-404050-NIC from Santa Cruz Biotechnology
|
||||||||
CLC-KA Double Nickase Plasmid (h2) - sc-404050-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CLC-KA CRISPR Activation Plasmid (h) - sc-404050-ACT from Santa Cruz Biotechnology
|
||||||||
CLC-KA CRISPR Activation Plasmid (h2) - sc-404050-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CLC-KA Lentiviral Activation Particles (h) - sc-404050-LAC from Santa Cruz Biotechnology
|
||||||||
CLC-KA Lentiviral Activation Particles (h2) - sc-404050-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CLC-KA siRNA (h) - sc-105209 from Santa Cruz Biotechnology
|
||||||||
CLC-KA shRNA Plasmid (h) - sc-105209-SH from Santa Cruz Biotechnology
|
||||||||
CLC-KA shRNA (h) Lentiviral Particles - sc-105209-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU126981 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN2191 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2191 from Sigma-Aldrich
|
||||||||
CLCNKA siRNA (Human) - CRH0849 from Cohesion Biosciences
|
||||||||
CLCNKA RNAi - H00001187-R01 from Novus Biologicals
|
||||||||
CLCNKA - MBS8222667 from MyBioSource
|
||||||||
shRNA set against Human CLCNKA (NM_004070.3) - SHH264605 from Creative biogene
|
||||||||
Human CLCNKA siRNA - orb261351 from Biorbyt
|
||||||||
CLCNKA shRNA Plasmid (Human) - CHH0849 from Cohesion Biosciences
|
||||||||
CLCNKA miRNA 3'UTR clone - MiUTR1H-02187 from Creative biogene
|
||||||||
CLCNKA miRNA 3'UTR clone - MiUTR1H-02188 from Creative biogene
|