INTS6

Gene Symbol INTS6
Entrez Gene 26512
Alt Symbol DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2
Species Human
Gene Type protein-coding
Description integrator complex subunit 6
Other Description DEAD box protein|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26|RNA helicase HDB|protein deleted in cancer 1
Swissprots Q9Y5M9 Q9UFK0 Q6PJP4 Q9UL03 Q0P664
Accessions CAC07726 CAF86852 EAX08873 EAX08874 EAX08875 EAX08876 EAX08877 EAX08878 EAX08879 EAX08880 EAX08881 Q9UL03 AA251444 AA262171 AF086440 AF097645 AAF03046 AF141326 AAD39481 AK074946 BAG52037 AK096696 BAG53352 AK128795 BAG54738 AK296801 BAG59375 AK303869 BAG64807 AK304218 BAG65090 AL117626 CAB56020 AL833524 AW967611 BC013358 AAH13358 BC018725 AAH18725 BC032386 AAH32386 BC039829 AAH39829 BC040581 BC094745 BE160101 BG621629 BK005730 DAA05730 BM699545 BU754174 BX116410 DA182797 FN136361 XM_005266340 XP_005266397 XM_005266341 XP_005266398 XM_011535040 XP_011533342 XM_011535041 XP_011533343 NM_001039937 NP_001035026 NM_001039938 NP_001035027 NM_001306091 NP_001293020 NM_012141 NP_036273
Function Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth. {ECO:0000269|PubMed:15254679, ECO:0000269|PubMed:16239144}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11939413}.
Tissue Specificity Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10467397}.

DICE1 (H-6) - sc-376524 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DICE1 (H-6): sc-376524. Western blot analysis of DICE1 expression in HeLa nuclear extract.

DICE1 (H-114) - sc-292600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DICE1 (H-114): sc-292600. Western blot analysis of DICE1 expression in HeLa (A) and DU 145 (B) nuclear extracts.

DICE1 (E-18) - sc-5876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DICE1 (V-20) - sc-5877 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DICE1 (LL7) - sc-101232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DICE1 (LL7): sc-101232. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing nuclear localization.

Anti-DDX26 antibody - ab86369 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human thyroid carcinoma tissue labelling DDX26 with ab86369 at 1/200 (1µg/ml). Detection: DAB.

Anti-DDX26 antibody - ab57069 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
DDX26 antibody (ab57069) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human testis.

Anti-DDX26 antibody - ab114075 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab114075 at 1/250 dilution staining DDX26 in Formalin-Fixed, Paraffin-Embedded prostate carcinoma tissue by Immunohistochemistry. Detection utilised DAB.

Anti-INTS6 Antibody (aa779-888, Azide-free) - LS-C327193 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-INTS6 Antibody - LS-C334844 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using INTS6 antibody.

Anti-INTS6 Antibody (aa756-805) - LS-C80157 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.

Anti-INTS6 Antibody (aa750-800) - LS-C286811 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human DDX26/DICE1 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-DDX26/DICE1 used at a dilution of 1:250.

Anti-INTS6 Antibody (aa750-800) - LS-C288448 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human DDX26/DICE1 by Immunohistochemistry. Sample: FFPE section of human thyroid carcinoma. Antibody: Affinity purified rabbit anti-DDX46/DICE1 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-INTS6 Antibody (clone 3D9) - LS-C133718 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D9
Immunoperoxidase of monoclonal antibody to DDX26 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]

INTS6 Antibody - NBP1-85302 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INTS6 Antibody - NB100-86990 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: INTS6 Antibody [NB100-86990] - Detection of Human INT6 NB100-86990. INT6 was also immunoprecipitated by another rabbit anti-INT6 antibody.

INTS6 Antibody - NBP1-88029 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: INTS6 Antibody [NBP1-88029] - Lane 1: Marker [kDa] 207, 110, 79, 49, 32, 25, 17.1. Lane 2: Human cell line RT-4. Lane 3: Human cell line EFO-21. Lane 4: Human cell line A-431. Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

INTS6 Antibody (3D9) - H00026512-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D9
Immunocytochemistry/Immunofluorescence: INTS6 Antibody (3D9) [H00026512-M02] - Analysis of monoclonal antibody to INTS6 on HeLa cell. Antibody concentration 10 ug/ml.

Anti-INTS6 antibody produced in rabbit - HPA001552 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-INTS6: <B>Cat. No. HPA001552</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human vulva/anal skin tissue showing nuclear staining of squamous epithelial cells.

Anti-INTS6 antibody produced in rabbit - SAB2101169 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-INTS6: <B>Cat. No.SAB2101169</B>: INTS6 in Placenta tissue lysate with INTS6 antibody at 1.0 μg/mL.

Monoclonal Anti-DDX26 antibody produced in mouse - WH0026512M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D9
<B>Immunoblotting</B><BR/>Monoclonal Anti-DDX26, <B>Cat. No. WH0026512M2</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.1 kDa using immunogen protein lysate.

Anti-INTS6 antibody produced in rabbit - HPA001846 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-INTS6: <B>Cat. No. HPA001846</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis shows moderate nuclear positivity in cells of seminiferous ducts.

INTS6 antibody - C-terminal region (ARP36404_P050) - ARP36404_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DDX26-Antibody-monoclonal-M02 - AT1734a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D9
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) .

EIF4A3 antibody - GTX115290 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-EIF4A3 antibody used in ICC/IF. GTX115290
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