| Gene Symbol | CTBP1 |
|---|---|
| Entrez Gene | 1487 |
| Alt Symbol | BARS |
| Species | Human |
| Gene Type | protein-coding |
| Description | C-terminal binding protein 1 |
| Other Description | C-terminal-binding protein 1|brefeldin A-ribosylated substrate |
| Swissprots | Q13363 Q4W5N3 Q7Z2Q5 |
| Accessions | AAY40989 EAW82599 EAW82600 EAW82601 EAW82602 Q13363 AF091555 AAD14597 AL137653 CAB70861 BC011655 AAH11655 BC053320 AAH53320 BC064333 BC072021 AAH72021 BC098400 AAH98400 BM989059 BU553431 DQ891918 ABM82844 DQ895102 ABM86028 KJ534818 AHW56458 KJ535006 AHW56645 KJ535043 AHW56682 KJ535050 AHW56689 KJ535065 AHW56704 KJ535066 AHW56705 KJ535067 AHW56706 U37408 AAC62822 XM_005272261 XP_005272318 XM_005272263 XP_005272320 XM_011513395 XP_011511697 XM_011513396 XP_011511698 XM_011513397 XP_011511699 NM_001012614 NP_001012632 NM_001328 NP_001319 |
| Function | Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. {ECO:0000269|PubMed:12419229, ECO:0000269|PubMed:15542832, ECO:0000269|PubMed:18212045, ECO:0000269|PubMed:19103759, ECO:0000269|PubMed:9858600}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12679040}. Nucleus {ECO:0000269|PubMed:12679040}. |
| Tissue Specificity | Expressed in germinal center B-cells. {ECO:0000269|PubMed:18212045}. |
| Top Pathways | Wnt signaling pathway, Notch signaling pathway, Chronic myeloid leukemia |