Gene Symbol | ADAMTS14 |
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Entrez Gene | 140766 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ADAM metallopeptidase with thrombospondin type 1 motif, 14 |
Other Description | A disintegrin and metalloproteinase with thrombospondin motifs 14|ADAM-TS 14|ADAM-TS14|ADAMTS-14|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 14|metalloprotease-disintegrin protease |
Swissprots | Q8TEY8 Q8TE55 Q5T4G0 Q8WXS8 Q5T4G1 |
Accessions | EAW54409 EAW54410 Q8WXS8 AF358666 AAL40229 AF366351 AAL79814 AJ345098 CAC87943 AK128469 BC140263 AAI40264 XM_011539300 XP_011537602 XM_011539301 XP_011537603 XM_011539302 XP_011537604 XM_011539303 XP_011537605 XM_011539304 XP_011537606 XM_011539305 XP_011537607 XM_011539306 XP_011537608 XM_011539307 XP_011537609 XM_011539308 XP_011537610 XM_011539309 XP_011537611 NM_080722 NP_542453 NM_139155 NP_631894 |
Function | Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Expressed in retina and at low levels in brain, lung and placenta. High expression in fetal tissues. |
ADAMTS-14 CRISPR/Cas9 KO Plasmid (h) - sc-406890 from Santa Cruz Biotechnology
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ADAMTS-14 HDR Plasmid (h) - sc-406890-HDR from Santa Cruz Biotechnology
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ADAMTS-14 Double Nickase Plasmid (h) - sc-406890-NIC from Santa Cruz Biotechnology
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ADAMTS-14 Double Nickase Plasmid (h2) - sc-406890-NIC-2 from Santa Cruz Biotechnology
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ADAMTS-14 CRISPR Activation Plasmid (h) - sc-406890-ACT from Santa Cruz Biotechnology
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ADAMTS-14 CRISPR Activation Plasmid (h2) - sc-406890-ACT-2 from Santa Cruz Biotechnology
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ADAMTS-14 Lentiviral Activation Particles (h) - sc-406890-LAC from Santa Cruz Biotechnology
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ADAMTS-14 Lentiviral Activation Particles (h2) - sc-406890-LAC-2 from Santa Cruz Biotechnology
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ADAMTS-14 siRNA (h) - sc-61950 from Santa Cruz Biotechnology
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ADAMTS-14 shRNA Plasmid (h) - sc-61950-SH from Santa Cruz Biotechnology
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ADAMTS-14 shRNA (h) Lentiviral Particles - sc-61950-V from Santa Cruz Biotechnology
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ADAMTS14 RNAi - H00140766-R01 from Novus Biologicals
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MISSION® esiRNA - EHU093521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2827 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2827 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09807 from Sigma-Aldrich
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ADAMTS14 siRNA (Human) - CRJ5318 from Cohesion Biosciences
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ADAMTS14 RNAi - H00140766-R02 from Novus Biologicals
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ADAMTS14 - MBS8202325 from MyBioSource
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shRNA set against Human ADAMTS14 (NM_080722.3) - SHH231770 from Creative biogene
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shRNA set against Human ADAMTS14(NM_139155.2) - SHG039655 from Creative biogene
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shRNA set against Human ADAMTS14(NM_080722.3) - SHG039673 from Creative biogene
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Human ADAMTS14 siRNA - orb275819 from Biorbyt
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ADAMTS14 shRNA Plasmid (Human) - CHJ5318 from Cohesion Biosciences
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ADAMTS14 miRNA 3'UTR clone - MiUTR1H-00169 from Creative biogene
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