Gene Symbol |
FBXO27
|
Entrez Gene |
126433
|
Alt Symbol |
FBG5, Fbx27
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
F-box protein 27
|
Other Description |
F-box only protein 27|F-box protein FBG5|F-box/G-domain protein 5
|
Swissprots |
Q8NI29 Q96C87
|
Accessions |
EAW56856 Q8NI29 AF436061 AAM27918 BC014527 AAH14527 BC030060 AAH30060 BX377760 HQ448139 ADQ32620 NM_178820 NP_849142
|
Function |
Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides. {ECO:0000269|PubMed:18203720}.
|
Tissue Specificity |
Predominantly expressed in brain, heart and kidney. Expressed at lower levels in liver and lung. {ECO:0000269|PubMed:12383498}.
|