MTHFR

Gene Symbol MTHFR
Entrez Gene 4524
Alt Symbol -
Species Human
Gene Type protein-coding
Description methylenetetrahydrofolate reductase (NAD(P)H)
Other Description 5,10-methylenetetrahydrofolate reductase (NADPH)|methylenetetrahydrofolate reductase
Swissprots Q7Z6M6 Q9UQR2 B2R7A6 P42898 Q5SNW9 Q8IU73 Q5SNW6
Accessions AAD17965 AAG33979 AAN40863 AAN40864 AAN40865 AAP88033 AAZ03741 ABB17330 ABK34493 CAB81551 CAB81552 EAW71708 EAW71709 P42898 AB209113 BAD92350 AJ237672 CAB41971 AK312907 BAG35753 AY046560 AAL17646 AY046561 AAL17647 AY046562 AAL17648 AY046563 AAL17649 AY046564 AAL17650 AY046565 AAL17651 BC011614 BC018766 BC053509 AAH53509 CN355286 JQ429447 AFQ62002 U09806 AAA74440 XM_005263458 XP_005263515 XM_005263460 XP_005263517 XM_005263461 XP_005263518 XM_005263462 XP_005263519 XM_005263463 XP_005263520 XM_011541495 XP_011539797 XM_011541496 XP_011539798 NM_005957 NP_005948
Function Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine.
Top Pathways Carbon metabolism, One carbon pool by folate

MTHFR (H-298) - sc-368720 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MTHFR (N-20) - sc-17079 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MTHFR antibody - ab55530 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55530 MTHFR antibody at 1ug/ml.

Anti-MTHFR antibody - ab129438 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MTHFR antibody (ab129438) at 0.4 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-MTHFR antibody - ab125707 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MTHFR antibody (ab125707) at 1/1000 dilution + A549 cell lysate at 30 µg

Anti-MTHFR antibody - ab96229 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MTHFR antibody (ab96229) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-MTHFR antibody - ab179934 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spleen tissue labeling MTHFR with ab179934 at 3.75 µg/ml.

Anti-MTHFR antibody [5D3] - ab113637 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5D3
Overlay histogram showing A549 cells stained with ab113637 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab113637, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in A549 cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-MTHFR Antibody (aa266-292, APC) - LS-C263655 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody (aa266-292, AP) - LS-C263656 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody (aa314-363) - LS-C199926 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of MTHFR antibody in extracts from COLO205 cells treated with Forskolin.

Anti-MTHFR Antibody (aa266-292, Biotin) - LS-C263657 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody (clone 2H9) - LS-C197716 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H9
Detection limit for recombinant GST tagged MTHFR is approximately 0.03 ng/ml as a capture antibody.

Anti-MTHFR Antibody (Arg363) - LS-C177293 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of MTHFR (R363) pAb in extracts from COLO205 cells treated with Forskolin.

Anti-MTHFR Antibody (aa266-292, FITC) - LS-C263658 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody - LS-C155174 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE MTHFR antibody diluted at 1:1000

Anti-MTHFR Antibody (aa266-292, Azide-free, HRP) - LS-C263660 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody (aa266-292) - LS-C157974 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MTHFR Antibody western blot of CEM cell line lysates (35 ug/lane). The MTHFR antibody detected the MTHFR protein (arrow).

Anti-MTHFR Antibody (aa369-383) - LS-C154913 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
MTHFR antibody (0.3 ug/ml) staining of NIH3T3 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MTHFR Antibody (aa21-248) - LS-C186306 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A:293T. 7.5% SDS PAGE. MTHFR antibody diluted at 1:1000.

Anti-MTHFR Antibody (aa266-292, PE) - LS-C263661 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody (aa266-292) - LS-C323149 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody (aa606-656) - LS-C286177 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MTHFR Antibody - LS-C330910 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot analysis of extracts of 293T cell line, using MTHFR antibody.

Anti-MTHFR Antibody (aa685-697) IHC-plus™ - LS-B9203 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-MTHFR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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