| Gene Symbol |
FPR3
|
| Entrez Gene |
2359
|
| Alt Symbol |
FML2_HUMAN, FMLPY, FPRH1, FPRH2, FPRL2, RMLP-R-I
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
formyl peptide receptor 3
|
| Other Description |
FMLP-R-II|FMLP-related receptor II|N-formyl peptide receptor 3|formyl peptide receptor-like 2
|
| Swissprots |
P25089
|
| Accessions |
AAA52474 AAC72102 AAP20654 EAW72045 P25089 AK123030 AK292541 BAF85230 BC059388 AAH59388 BC069070 AAH69070 BC069593 AAH69593 BC069812 AAH69812 CB996360 M76673 AAA58482 XM_011526687 XP_011524989 NM_002030 NP_002021
|
| Function |
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Staphylococcus aureus infection, Neuroactive ligand-receptor interaction
|