Gene Symbol | FPR3 |
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Entrez Gene | 2359 |
Alt Symbol | FML2_HUMAN, FMLPY, FPRH1, FPRH2, FPRL2, RMLP-R-I |
Species | Human |
Gene Type | protein-coding |
Description | formyl peptide receptor 3 |
Other Description | FMLP-R-II|FMLP-related receptor II|N-formyl peptide receptor 3|formyl peptide receptor-like 2 |
Swissprots | P25089 |
Accessions | AAA52474 AAC72102 AAP20654 EAW72045 P25089 AK123030 AK292541 BAF85230 BC059388 AAH59388 BC069070 AAH69070 BC069593 AAH69593 BC069812 AAH69812 CB996360 M76673 AAA58482 XM_011526687 XP_011524989 NM_002030 NP_002021 |
Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Staphylococcus aureus infection, Neuroactive ligand-receptor interaction |
FPR3 / FPRL2 Antibody Blocking Peptide - LS-E2084 from LifeSpan Bioscience
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FPR3 / FPRL2 Blocking Peptide - LS-E28895 from LifeSpan Bioscience
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FPR3 / FPRL2 Antibody Blocking Peptide - LS-E28802 from LifeSpan Bioscience
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FPR3 / FPRL2 Antibody Blocking Peptide - LS-E28803 from LifeSpan Bioscience
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FPR3 / FPRL2 Antibody Blocking Peptide - LS-E26492 from LifeSpan Bioscience
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FPR3 / FPRL2 Antibody Blocking Peptide - LS-E9784 from LifeSpan Bioscience
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FPR3-Antibody-C-term-Blocking-peptide - BP12974b from Abgent, a WuXi AppTec company
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FPRL2-Antibody-Center-Blocking-Peptide - BP8793c from Abgent, a WuXi AppTec company
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FPR3 Blocking Peptide - abx161106 from Abbexa
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FPR3 Blocking Peptide - abx161107 from Abbexa
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FPR3 Peptide - AC21-2807-P from Abcore
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FMLP-related receptor II - H00002359-G01 from Acris Antibodies
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FMLP-related receptor II - H00002359-Q01-10 from Acris Antibodies
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FMLP-related receptor II - H00002359-Q01-25 from Acris Antibodies
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FPR3 fusion protein - ag12852 from Proteintech Group
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FPR3 Blocking Peptide - CBP3605 from Cohesion Biosciences
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FPR3 Blocking Peptide - CBP3606 from Cohesion Biosciences
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Recombinant Human FPRL2/FPR3 Protein - H00002359-G01 from Novus Biologicals
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Formyl Peptide Receptor-like 2, Peptide - MBS427861 from MyBioSource
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FPR3 Peptide, Human - M34GP05889H from Creative Peptides
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N-formyl peptide receptor 3 (FPR3), Recombinant Protein - MBS7014995 from MyBioSource
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N-formyl peptide receptor 3 (FPR3), Recombinant Protein - MBS966001 from MyBioSource
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