CENPA

Gene Symbol	CENPA
Entrez Gene	1058
Alt Symbol	CENP-A, CenH3
Species	Human
Gene Type	protein-coding
Description	centromere protein A
Other Description	centromere autoantigen A|centromere protein A, 17kDa|centromere-specific histone|histone H3-like centromeric protein A
Swissprots	Q53T74 P49450 D6W544 Q9BVW2
Accessions	AAB47505 AAX93267 EAX00669 EAX00670 EAX00671 EAX00672 P49450 BC000881 AAH00881 BC002703 AAH02703 BC011013 BT007246 AAP35910 HQ448742 ADQ33220 JF432571 ADZ15788 U14518 AAA57416 NM_001042426 NP_001035891 NM_001809 NP_001800
Function	Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro). {ECO:0000269|PubMed:20739937, ECO:0000269|PubMed:21478274}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. Occupies a compact domain at the inner kinetochore plate stretching across 2 thirds of the length of the constriction but encompassing only one third of the constriction width and height.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CENPA (unmodified ) peptide - ab13566 from Abcam Category Peptide

Human CENPA full length protein - ab73635 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human CENPA peptide - ab21455 from Abcam Category Peptide

Human CENPA peptide - ab33564 from Abcam Category Peptide

CENPA / CENP-A Antibody Blocking Peptide - LS-E2750 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CENPA / CENP-A Antibody Blocking Peptide - LS-E16774 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CENPA Protein - H00001058-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CENPA-Antibody-Center-Blocking-peptide - BP13843c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CENPA Protein (OPPA01301) - OPPA01301 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Sf9 Insect Cells

Human CENPA protein - orb81023 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CENPA Blocking Peptide - 33R-6060 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CENPA Blocking Peptide - 33R-1362 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CENPA Blocking Peptide - abx161347 from Abbexa Category Peptide Species Human, Mouse, Rat

CENP-A - H00001058-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CENP-A - H00001058-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Centromere Protein A, Human Recombinant - 228-10216-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Sf9 insect cells. Species Human

Recombinant Human CENPA - 228-10216-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Sf9 insect cells. Species Human

Recombinant Human CENPA - 228-10216-3 from RayBiotech Category Protein Source Sf9 insect cells. Species Human

CENPA fusion protein - ag13187 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CENPA Human - PRPS-396 from NeoScientific Category Protein Prices $65.00, $169.00, $5,070.00 Sizes 5 µg, 20 µg, 1 mg Source Sf9 insect cells. Species Human

Recombinant Human Centromere Protein A - BP001879-PRO-389 from Syd Labs Category Protein Prices $160.00, $3,900.00 Sizes 20 µg, 1 mg Source Sf9 insect cells-derived. Species Human

CENP-A Human - GWB-E92648 from Genway Biotech Category Protein Prices $75.00, $165.00, $4,375.00 Sizes 5 μg, 20 μg, 1000 μg Species Human

Recombinant Human CENPA, His-tagged - CENPA-27391TH from Creative Biomart Category Protein

Recombinant Human Centromere Protein A, His-tagged - CENPA-617H from Creative Biomart Category Protein Source Sf9 insect cells .

Centromere Protein A Human - NKX-746 from Reagent Proteins Category Protein Prices $348.00, $4,060.00 Sizes 20.00 µg, 1 mg Source Sf9 insect cells Species Human

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