| Gene Symbol |
ATG9B
|
| Entrez Gene |
285973
|
| Alt Symbol |
APG9L2, NOS3AS, SONE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
autophagy related 9B
|
| Other Description |
APG9-like 2|ATG9 autophagy related 9 homolog B|autophagy 9-like 2 protein|autophagy-related protein 9B|endothelial nitric oxide synthase antisense|nitric oxide synthase 3-overlapping antisense gene protein
|
| Swissprots |
Q8N8I8 Q674R7 A1A5D3 Q6JRW5
|
| Accessions |
Q674R7 AI221785 AI243432 AI827483 AK096734 BAC04853 AY316116 AAQ86941 AY515311 AAS87212 BC128587 AAI28588 BK004019 DAA05200 XM_011516064 XP_011514366 XM_011516065 XP_011514367 XM_011516066 XP_011514368 NM_173681 NP_775952 NR_073169
|
| Function |
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:18936157}; Multi-pass membrane protein {ECO:0000269|PubMed:18936157}. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation- induced redistribution depends on ULK1 and ATG13.
|
| Tissue Specificity |
Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial. {ECO:0000269|PubMed:15234981}.
|