| Gene Symbol | CDO1 |
|---|---|
| Entrez Gene | 1036 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | cysteine dioxygenase type 1 |
| Other Description | CDO|CDO-I|cysteine dioxygenase, type I |
| Swissprots | Q8TB64 Q6FHZ8 B2RAK4 P78513 Q16878 |
| Accessions | AAB58352 BAA12873 EAW48957 Q16878 AK130357 AK314231 BAG36901 AL534761 BC024241 AAH24241 BX336206 CR536540 CAG38777 D85777 BAA12872 DQ891652 ABM82578 HQ448366 ADQ32846 Z23010 CAA80552 Z31357 CAA83234 XR_427700 NM_001801 NP_001792 |
| Function | Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. |
| Tissue Specificity | Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells. {ECO:0000269|PubMed:10427686}. |
| Top Pathways | Cysteine and methionine metabolism, Taurine and hypotaurine metabolism |