Gene Symbol | HIST1H2BN |
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Entrez Gene | 8341 |
Alt Symbol | H2B/d, H2BFD |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bn |
Other Description | H2B histone family, member D|histone 1, H2bn|histone H2B type 1-N|histone H2B.d |
Swissprots | Q99877 B2R5L4 Q96FB7 Q494S8 |
Accessions | AAN06697 CAB05938 EAX03114 EAX03115 EAX03116 EAX03117 Q99877 AK312228 BAG35161 BC009783 BC011372 BC101411 AAI01412 BC101412 AAI01413 BC101413 AAI01414 DQ891028 ABM81954 DQ894207 ABM85133 NM_003520 NP_003511 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BN CRISPR/Cas9 KO Plasmid (h) - sc-411144 from Santa Cruz Biotechnology
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Histone cluster 1 H2BN HDR Plasmid (h) - sc-411144-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BN Double Nickase Plasmid (h) - sc-411144-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BN Double Nickase Plasmid (h2) - sc-411144-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BN CRISPR Activation Plasmid (h) - sc-411144-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BN CRISPR Activation Plasmid (h2) - sc-411144-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BN Lentiviral Activation Particles (h) - sc-411144-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BN Lentiviral Activation Particles (h2) - sc-411144-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BN siRNA (h) - sc-105484 from Santa Cruz Biotechnology
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Histone cluster 1 H2BN shRNA Plasmid (h) - sc-105484-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BN shRNA (h) Lentiviral Particles - sc-105484-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10081 from Sigma-Aldrich
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HIST1H2BN siRNA (Human) - CRH5461 from Cohesion Biosciences
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HIST1H2BN RNAi - H00008341-R01 from Novus Biologicals
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HIST1H2BN - MBS8200952 from MyBioSource
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shRNA set against Human HIST1H2BN (NM_003520.3) - SHH312665 from Creative biogene
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shRNA set against Human HIST1H2BN(NM_003520.3) - SHH122681 from Creative biogene
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Human HIST1H2BN siRNA - orb265963 from Biorbyt
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HIST1H2BN shRNA Plasmid (Human) - CHH5461 from Cohesion Biosciences
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HIST1H2BN miRNA 3'UTR clone - MiUTR1H-04541 from Creative biogene
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