GSTA4

Gene Symbol GSTA4
Entrez Gene 2941
Alt Symbol GSTA4-4, GTA4
Species Human
Gene Type protein-coding
Description glutathione S-transferase alpha 4
Other Description GST class-alpha member 4|S-(hydroxyalkyl)glutathione lyase A4|glutathione S-alkyltransferase A4|glutathione S-aralkyltransferase A4|glutathione S-aryltransferase A4|glutathione S-transferase A4|glutathione S-transferase A4-4|glutathione transferase A4-4
Swissprots Q9H414 O15217 Q9BX18 Q6P4G1 B2RD15 Q5T7Q8
Accessions AAC72706 AAW56075 EAX04393 EAX04394 EAX04395 EAX04396 EAX04397 EAX04398 EAX04399 O15217 AA709059 AF020918 AAD04711 AF025887 AAC39695 AF125271 AAD27704 AF125272 AAD27705 AF125273 AAD27706 AK054804 BAG51425 AK315369 BAG37762 BC015523 AAH15523 BC063439 AAH63439 BC096817 BG716171 CR749474 CAH18304 DA521337 DQ890661 ABM81587 DQ893841 ABM84767 Y13047 CAA73482 XM_005249035 XP_005249092 XM_011514534 XP_011512836 XM_011514535 XP_011512837 NM_001512 NP_001503
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE). {ECO:0000269|PubMed:10329152, ECO:0000269|PubMed:20085333}.
Subcellular Location Cytoplasm.
Tissue Specificity Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver.
Top Pathways Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

GSTA4 (P-13) - sc-241483 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GSTA4 (Q-12) - sc-241484 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GSTA4 antibody - ab66974 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-GSTA4 antibody (ab66974) at 1/500 dilutionLane 1 : GSTA4 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-GSTA4 antibody [1E2] - ab117916 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E2
Overlay histogram showing HepG2 cells stained with ab117916 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab117916, 1/50 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H+L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-GSTA4 antibody [EPR8404(B)] - ab134919 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8404(B)
All lanes : Anti-GSTA4 antibody [EPR8404(B)] (ab134919) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human fetal liver lysateLane 3 : 293T cell lysateLane 4 : HepG2 cell lysateLane 5 : JAR cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-GSTA4 antibody - N-terminal - ab175979 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (N-Terminus) - LS-C121895 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa69-98, AP) - LS-C277664 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa69-98, APC) - LS-C277665 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa69-98, Biotin) - LS-C277666 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa69-98, Azide-free, HRP) - LS-C277668 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa69-98, FITC) - LS-C277667 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa69-98, PE) - LS-C277669 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (N-Terminus, clone EPR8404(B)) - LS-C154693 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8404(B)
Western blot analysis on (A) fetal brain, (B) fetal liver, (C) 293T, (D) HepG2, and (E) JAR cell lysates using anti-GSTA4 antibody.

Anti-GSTA4 Antibody (aa1-222, Biotin) - LS-C301116 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa3-222, Biotin) - LS-C297556 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa1-222, FITC) - LS-C302138 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa23-72) - LS-C146264 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GSTA4 antibody LS-C146264 Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-GSTA4 Antibody (aa3-222, FITC) - LS-C305615 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody - LS-C308133 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GSTA4 Antibody (C-Terminus) - LS-C81258 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-GSTA4 Antibody - LS-C310533 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GSTA4 Antibody (aa1-222) - LS-C294257 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant GSTA4.

Anti-GSTA4 Antibody (aa3-222) - LS-C294255 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant GSTA4.

Anti-GSTA4 Antibody (aa2-222) - LS-C314580 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant GSTA4.
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