Gene Symbol |
GNL2
|
Entrez Gene |
29889
|
Alt Symbol |
HUMAUANTIG, NGP1, Ngp-1, Nog2, Nug2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
guanine nucleotide binding protein-like 2 (nucleolar)
|
Other Description |
autoantigen NGP-1|novel nucleolar guanosine 5'-triphosphate binding protein autoantigen|nucleolar G-protein gene 1|nucleolar GTP-binding protein 2|nucleolar GTPase|nucleostemin-2
|
Swissprots |
Q13823 Q9BWN7
|
Accessions |
EAX07333 Q13823 AA766044 AK130697 AK298358 BAG60601 AK307352 AK312915 BAG35761 BC000107 AAH00107 BC009250 AAH09250 DB452094 DQ892183 ABM83109 EU176692 ABW03493 L05425 AAC37588 XM_011541300 XP_011539602 NM_013285 NP_037417
|
Function |
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. {ECO:0000250}.
|
Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
|
Tissue Specificity |
Ubiquitously expressed at relatively low levels in all human tissues tested, with the highest level of expression in the testes.
|
Top Pathways |
Ribosome biogenesis in eukaryotes
|