Gene Symbol | GNL2 |
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Entrez Gene | 29889 |
Alt Symbol | HUMAUANTIG, NGP1, Ngp-1, Nog2, Nug2 |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein-like 2 (nucleolar) |
Other Description | autoantigen NGP-1|novel nucleolar guanosine 5'-triphosphate binding protein autoantigen|nucleolar G-protein gene 1|nucleolar GTP-binding protein 2|nucleolar GTPase|nucleostemin-2 |
Swissprots | Q13823 Q9BWN7 |
Accessions | EAX07333 Q13823 AA766044 AK130697 AK298358 BAG60601 AK307352 AK312915 BAG35761 BC000107 AAH00107 BC009250 AAH09250 DB452094 DQ892183 ABM83109 EU176692 ABW03493 L05425 AAC37588 XM_011541300 XP_011539602 NM_013285 NP_037417 |
Function | GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. {ECO:0000250}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
Tissue Specificity | Ubiquitously expressed at relatively low levels in all human tissues tested, with the highest level of expression in the testes. |
Top Pathways | Ribosome biogenesis in eukaryotes |
GNL2 CRISPR/Cas9 KO Plasmid (h) - sc-405909 from Santa Cruz Biotechnology
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GNL2 HDR Plasmid (h) - sc-405909-HDR from Santa Cruz Biotechnology
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GNL2 Double Nickase Plasmid (h) - sc-405909-NIC from Santa Cruz Biotechnology
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GNL2 Double Nickase Plasmid (h2) - sc-405909-NIC-2 from Santa Cruz Biotechnology
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GNL2 CRISPR Activation Plasmid (h) - sc-405909-ACT from Santa Cruz Biotechnology
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GNL2 CRISPR Activation Plasmid (h2) - sc-405909-ACT-2 from Santa Cruz Biotechnology
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GNL2 Lentiviral Activation Particles (h) - sc-405909-LAC from Santa Cruz Biotechnology
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GNL2 Lentiviral Activation Particles (h2) - sc-405909-LAC-2 from Santa Cruz Biotechnology
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GNL2 siRNA (h) - sc-62685 from Santa Cruz Biotechnology
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GNL2 shRNA Plasmid (h) - sc-62685-SH from Santa Cruz Biotechnology
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GNL2 shRNA (h) Lentiviral Particles - sc-62685-V from Santa Cruz Biotechnology
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GNL2 RNAi - H00029889-R01 from Novus Biologicals
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MISSION® esiRNA - EHU030771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9436 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9436 from Sigma-Aldrich
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GNL2 siRNA (Human) - CRH9250 from Cohesion Biosciences
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GNL2 - MBS8201555 from MyBioSource
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shRNA set against Human Gnl2 (NM_013285.2) - SHH304982 from Creative biogene
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GNL2 shRNA Plasmid (Human) - CHH9250 from Cohesion Biosciences
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GNL2 miRNA 3'UTR clone - MiUTR3H-10561 from Creative biogene
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