HEPACAM

Gene Symbol HEPACAM
Entrez Gene 220296
Alt Symbol GlialCAM, MLC2A, MLC2B
Species Human
Gene Type protein-coding
Description hepatic and glial cell adhesion molecule
Other Description hepatocyte cell adhesion molecule|protein hepaCAM
Swissprots Q8N7I3 Q8ND35 Q6ZWL4 Q67IP8 Q14CZ8
Accessions EAW67614 EAW67615 EAW67616 Q14CZ8 AK098396 BAC05297 AK122595 BAC85486 AL834419 CAD39081 AY047587 AAQ93018 BC037810 BC104831 AAI04832 BC113562 AAI13563 DA239226 XM_005271449 XP_005271506 XM_006718786 XP_006718849 XM_011542669 XP_011540971 NM_152722 NP_689935
Function Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}. Membrane; Single-pass type I membrane protein; Cytoplasmic side {ECO:0000269|PubMed:15885354, ECO:0000269|PubMed:15917256}. Note=In MCF-7 breast carcinoma and hepatic Hep 3B2.1-7 and Hep-G2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent cells, localized predominantly to the cytoplasmic membrane, particularly in areas of cell-cell contacts. Colocalizes with CDH1.

HepaCAM (G-15) - sc-168078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HepaCAM (G-15): sc-168078. Western blot analysis of HepaCAM expression in Hep G2 (A), HeLa (B) and HT-1080 (C) whole cell lysates and human breast tissue extract (D).

HepaCAM (N-13) - sc-168079 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HEPACAM antibody - ab130769 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of HEPACAM staining in Human normal liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab130769, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-HEPACAM antibody - ab99122 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HEPACAM antibody (ab99122) at 1 µg/ml + HT1080 cell lysate at 10 µg

Anti-HEPACAM antibody [EPR11217] - ab172635 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11217
All lanes : Anti-HEPACAM antibody [EPR11217] (ab172635) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : Human fetal liver lysateLane 3 : Human stomach lysateLane 4 : Human fetal brain lysateLysates/proteins at 10 µg per lane.

Anti-HEPACAM Antibody (aa34-242) - LS-C36648 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327, AP) - LS-C222716 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327, APC) - LS-C222718 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327, Biotin) - LS-C222719 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327, FITC) - LS-C222720 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327, Azide-free, HRP) - LS-C222721 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327, PE) - LS-C222722 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa305-335) - LS-C321925 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM Antibody (aa298-327) - LS-C166837 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HEPACAM Antibody western blot of HepG2 cell line lysates (35 ug/lane). The HEPACAM antibody detected the HEPACAM protein (arrow).

Anti-HEPACAM Antibody (aa107-156) - LS-C111659 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HEPACAM antibody LS-C111659 Western blot of HT1080 cell lysate.

HepaCAM Antibody (419305) [Unconjugated] - MAB4108 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 419305
Western blot shows lysates of human brain (motor cortex) tissue and human brain (hippocampus) tissue. PVDF membrane was probed with 0.25 µg/mL of Mouse Anti-Human HepaCAM Monoclonal Antibody (Catalog # MAB4108) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for HepaCAM at approximately 45-70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

HepaCAM Antibody [Unconjugated] - AF4108 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of human brain (motor cortex) tissue and human brain (hippocampus) tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human HepaCAM Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4108) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for HepaCAM at approximately 45-70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

HepaCAM Antibody - NBP1-83558 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HEPACAM Antibody [NBP1-83558] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4

HepaCAM Antibody - NBP1-60020 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HEPACAM Antibody [NBP1-60020] - HT1080 cell lysate, concentration 0.2-1 ug/ml.

HepaCAM Antibody [Biotin] - BAF4108 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

TIP47 Polyclonal Antibody - bs-2914R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat liver  labeled with Anti-TIP47/M6PRBP1 Polyclonal Antibody, Unconjugated (bs-2914R)  followed by conjugation to the secondary antibody and DAB staining

HEPACAM Polyclonal Antibody - bs-5840R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HEPACAM, (N-terminal) antibody produced in rabbit - SAB2105976 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HEPACAM (N-Terminal): <B>Cat. No. SAB2105976</B>: HEPACAM in HT1080 cell lysates with HEPACAM antibody at 1.0 μg/mL.

ANTI-HEPACAM(C-TERMINAL) antibody produced in rabbit - SAB1305117 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HEPACAM (C-term): <B>Cat. No. SAB1305117</B>: HEPACAM Antibody (C-term) western blot analysis in HepG2 cell line lysates (35 μg/lane).

HEPACAM antibody - N-terminal region (ARP55504_P050) - ARP55504_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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