GABRA5

Gene Symbol GABRA5
Entrez Gene 2558
Alt Symbol -
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, alpha 5
Other Description GABA(A) receptor subunit alpha-5|gamma-aminobutyric acid receptor subunit alpha-5
Swissprots Q9NYT4 Q9NYT3 Q53XL6 P31644 Q14DC2 A8K338 Q9NYT5
Accessions AAB22608 AAC31809 AAF62508 AAF62509 AAF62510 EAW57656 EAW57657 P31644 A28104 CAA01920 AK124673 AK290453 BAF83142 AK294303 BAG57584 AK303742 BAG64714 BC011403 BC111979 AAI11980 BC113422 AAI13423 BT009830 AAP88832 DA157081 DB506215 DQ894267 ABM85193 EU176251 ABW03702 HQ258419 ADR83173 L08485 AAA58490 R49008 XM_005268258 XP_005268315 XM_006720459 XP_006720522 NM_000810 NP_000801 NM_001165037 NP_001158509
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction