| Gene Symbol |
BECN2
|
| Entrez Gene |
441925
|
| Alt Symbol |
BECN1L1, BECN1P1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
beclin 2
|
| Other Description |
Beclin-1-like protein 1|beclin 1, autophagy related, pseudogene 1|beclin-1 autophagy-related pseudogene 1|beclin-2
|
| Swissprots |
A8MW95 E9KNW0
|
| Accessions |
A8MW95 HM031116 ADM47406 NM_001290693 NP_001277622
|
| Function |
Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. {ECO:0000269|PubMed:23954414}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}.
|
| Tissue Specificity |
Present in fetal and adult brain (at protein level). {ECO:0000269|PubMed:23954414}.
|