| Gene Symbol |
GRIK3
|
| Entrez Gene |
2899
|
| Alt Symbol |
EAA5, GLR7, GLUR7, GluK3, GluR7a
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutamate receptor, ionotropic, kainate 3
|
| Other Description |
dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))|excitatory amino acid receptor 5|gluR-7|glutamate receptor 7|glutamate receptor ionotropic, kainate 3
|
| Swissprots |
A9Z1Z8 Q13003 Q16136 Q13004 B1AMS6
|
| Accessions |
AAB30157 AAC50421 CAC40655 CAC40656 CAC40657 EAX07350 EAX07351 Q13003 AJ249210 CAC80548 AJ299451 CAC44965 AW898512 BC156721 AAI56722 BG057125 BG818719 BI544689 BQ446793 DR003075 DT217951 U16127 AAB60407 XM_011541294 XP_011539596 XM_011541295 XP_011539597 NM_000831 NP_000822
|
| Function |
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Glutamatergic synapse, Neuroactive ligand-receptor interaction
|