| Gene Symbol | Hsd17b7 |
|---|---|
| Entrez Gene | 15490 |
| Alt Symbol | AI266814, ERG27 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | hydroxysteroid (17-beta) dehydrogenase 7 |
| Other Description | 17-beta-HSD 7|17-beta-hydroxysteroid dehydrogenase 7|3-keto-steroid reductase|estradiol 17-beta-dehydrogenase 7 |
| Swissprots | Q921L1 Q8K5C9 O88736 |
| Accessions | AAM21211 CAC88119 EDL39167 EDL39168 O88736 AK028380 BAC25918 AK050211 BAC34124 AK077914 BAC37061 AK194513 AK197256 BB767054 BC011464 BY228199 Y15733 CAA75742 XM_006496667 XP_006496730 XM_011238758 XP_011237060 NM_010476 NP_034606 |
| Function | Responsible for the reduction of the keto group on the C-3 of sterols. |
| Subcellular Location | Cell membrane; Single-pass membrane protein. |
| Tissue Specificity | Most abundant in ovaries of pregnant animals. Present also in nonpregnant animals in ovaries, mammary gland, liver, kidney and testis. |
| Top Pathways | Steroid hormone biosynthesis, Ovarian steroidogenesis, Steroid biosynthesis |