CPQ

Gene Symbol CPQ
Entrez Gene 10404
Alt Symbol LDP, PGCP
Species Human
Gene Type protein-coding
Description carboxypeptidase Q
Other Description Ser-Met dipeptidase|aminopeptidase|blood plasma glutamate carboxypeptidase|lysosomal dipeptidase
Swissprots B2RD88 Q9UNM8 Q9Y646 Q8NBZ1 Q9Y5X6
Accessions EAW91757 EAW91758 Q9Y646 AA492294 AF107833 AAD43213 AF107834 AAD43214 AF119386 AAD31418 AK075132 BAC11423 AK296013 BAG58784 AK304008 BAG64924 AK315447 BAG37835 BC012019 BC020689 AAH20689 BF445505 DA699663 DQ893177 ABM84103 DQ896759 ABM87758 XM_005250755 XP_005250812 XM_006716498 XP_006716561 XM_011516793 XP_011515095 XM_011516794 XP_011515096 XR_428374 XR_928286 NM_016134 NP_057218
Function Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
Subcellular Location Endoplasmic reticulum {ECO:0000269|PubMed:10206990}. Golgi apparatus {ECO:0000269|PubMed:10206990}. Lysosome {ECO:0000250}. Secreted {ECO:0000269|PubMed:10206990}. Note=Secretion is stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin. {ECO:0000250}.
Tissue Specificity Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level). {ECO:0000269|PubMed:10206990}.

PGCP (K-18) - sc-98073 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PGCP (V-12) - sc-98074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PGCP antibody - ab96159 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PGCP antibody (ab96159) at 1/500 dilution + Raji whole cell lysate at 30 µg

Anti-PGCP antibody - ab70507 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PGCP antibody (ab70507) at 1/500 dilutionLane 1 : PGCP transfected 293T lysateLane 2 : Non transfected 293T lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PGCP antibody - ab98047 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PGCP antibody (ab98047) at 1 µg/ml + NCI-H226 cell lysate at 10 µg

Anti-PGCP / Aminopeptidase Antibody (aa19-296) - LS-C185536 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
PGCP antibody detects PGCP protein at cytosol on U373 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U373 xenograft. PGCP antibody dilution:1:500.

Anti-PGCP / Aminopeptidase Antibody (aa19-470) - LS-C38160 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PGCP / Aminopeptidase Antibody (aa71-120) - LS-C107645 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PGCP / Aminopeptidase antibody LS-C107645 Western blot of NCI-H226 cell lysate.

PGCP Antibody - NBP1-58037 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PGCP Antibody [NBP1-58037] - NCI-H226 cell lysate, concentration 0.2-1 ug/ml.

PGCP Antibody - NBP1-32328 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PGCP Antibody - NBP1-87457 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PGCP Antibody - H00010404-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PGCP Antibody [H00010404-B01P] - Analysis of PGCP expression in transfected 293T cell line by PGCP polyclonal antibody. Lane 1: PGCP transfected lysate(51.92 KDa). Lane 2: Non-transfected lysate.

PGCP Polyclonal Antibody - bs-9917R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PGCP, (N-terminal) antibody produced in rabbit - SAB2104836 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PGCP, antibody produced in rabbit: <B>Cat. No. SAB2104836</B>: Immunoblotting analysis of PGCP in NCI-H226 cell lysate with PGCP anitbody at 1 μg/mL.

Anti-CPQ antibody produced in rabbit - HPA023235 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AP003117.2: <B>Cat. No. HPA023235</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Anti-CPQ antibody produced in rabbit - HPA024490 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AP003117.2: <B>Cat. No. HPA024490</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity with a granular pattern in subsets of tubuli.

Anti-PGCP antibody produced in mouse - SAB1406986 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PGCP: <B>Cat. No. SAB1406986</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~51.9 kDa using PGCP transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

PGCP antibody - N-terminal region (ARP48355_P050) - ARP48355_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Mouse PGCP Antibody - AF4258 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat

Mouse PGCP Affinity Purified Polyclonal Ab, Goat IgG - AF4258-SP from R&D Systems

Host Goat
Clonality Polyclonal

PGCP antibody - orb69770 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:Raji whole cell lysate using PGCP antibody

CPQ antibody (OAGA00229) - OAGA00229 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PGCP antibody - 70R-12720 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PGCP antibody - 70R-5467 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PGCP antibody - 16601-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human placenta tissue were subjected to SDS PAGE followed by western blot with 16601-1-AP(PGCP antibody) at dilution of 1:800
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