Gene Symbol | SMARCC1 |
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Entrez Gene | 6599 |
Alt Symbol | BAF155, CRACC1, Rsc8, SRG3, SWI3 |
Species | Human |
Gene Type | protein-coding |
Description | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 |
Other Description | BRG1-associated factor 155|SWI/SNF complex 155 kDa subunit|SWI/SNF complex subunit SMARCC1|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1|chromatin remodeling complex BAF155 subunit|mammalian chromatin remodeling complex BRG1-associated factor 155 |
Swissprots | Q6P172 Q17RS0 Q92922 Q8IWH2 |
Accessions | EAW64831 EAW64832 Q92922 AK302412 BAG63721 AK302541 BAG63813 BC012101 BC021862 AAH21862 BC032564 AAH32564 BC039843 AAH39843 BC040242 BC050564 AAH50564 BC065253 AAH65253 BC113465 AAI13466 BC117213 AAI17214 BG474088 BM971095 EU832157 ACE87507 EU832251 ACE86821 U66615 AAC50693 XM_011534034 XP_011532336 XM_011534035 XP_011532337 NM_003074 NP_003065 |
Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in brain, heart, muscle, placenta, lung, liver, muscle, kidney and pancreas. |
Human SMARCC1 peptide - ab24351 from Abcam
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Human SMARCC1 protein fragment - ab152694 from Abcam
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SMARCC1 / SWI3 Antibody Blocking Peptide - LS-E11745 from LifeSpan Bioscience
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SMARCC1 Partial Recombinant Protein - H00006599-Q01 from Novus Biologicals
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Human SMARCC1 protein - orb244883 from Biorbyt
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Human SMARCC1 protein - orb246949 from Biorbyt
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SMARCC1 / BAF155 - H00006599-Q01-10 from Acris Antibodies
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SMARCC1 / BAF155 - H00006599-Q01-25 from Acris Antibodies
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SMARCC1 fusion protein - ag12109 from Proteintech Group
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Recombinant Human SWI/SNF complex subunit SMARCC1(SMARCC1) ,partial - CSB-YP821715HU CSB-EP821715HU CSB-MP821715HU from Cusabio
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Recombinant human SWI/SNF complex subunit SMARCC1 - CSB-EP821715HU from Cusabio
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SMARCC1 Recombinant Protein Antigen - NBP1-88721PEP from Novus Biologicals
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SMARCC1 Protein - NBP1-88720PEP from Novus Biologicals
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SMARCC1-Antibody-N-term-Blocking-Peptide - BP5097a from Abgent, a WuXi AppTec company
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SMARCC1-Blocking-Peptide-C-term - BP21365b from Abgent, a WuXi AppTec company
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SMARCC1 Peptide, Human - M34GP14729H from Creative Peptides
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SMARCC1 Recombinant Protein (OPCA02360) - OPCA02360 from Aviva Systems Biology
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SMARCC1 Recombinant Protein (OPCA03633) - OPCA03633 from Aviva Systems Biology
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Recombinant human SWI/SNF complex subunit SMARCC1 - AP71405 from Signalway Antibody
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Recombinant Human SWI/SNF complex subunit SMARCC1(SMARCC1) ,partial - AP73166 from Signalway Antibody
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SWI/SNF complex subunit SMARCC1, Recombinant Protein - MBS1443404 from MyBioSource
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SWI/SNF complex subunit SMARCC1, Recombinant Protein - MBS9421269 from MyBioSource
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SWI/SNF complex subunit SMARCC1 (SMARCC1), Recombinant Protein - MBS9422854 from MyBioSource
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Recombinant Human SMARCC1 Protein (449-669 aa), His-SUMO-tagged - SMARCC1-1068H from Creative Biomart
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Recombinant Human SMARCC1 Protein (449-669 aa), His-tagged - SMARCC1-2741H from Creative Biomart
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