| Gene Symbol |
PLA2G7
|
| Entrez Gene |
7941
|
| Alt Symbol |
LDL-PLA2, LP-PLA2, PAFAD, PAFAH
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
|
| Other Description |
1-alkyl-2-acetylglycerophosphocholine esterase|2-acetyl-1-alkylglycerophosphocholine esterase|LDL-PLA(2)|LDL-associated phospholipase A2|PAF 2-acylhydrolase|PAF acetylhydrolase|gVIIA-PLA2|group-VIIA phospholipase A2|lipoprotein-associated phospholipase A2|platelet-activating factor acetylhydrolase
|
| Swissprots |
Q15692 Q5VTT1 A5HTT5 Q13093 Q8IVA2
|
| Accessions |
ABQ01234 EAX04301 EAX04302 Q13093 AK290381 BAF83070 AK294471 BAG57699 AK297066 BAG59587 BC025674 BC038452 AAH38452 BP326231 HQ448549 ADQ33028 U20157 AAC50126 U24577 AAB04170 XM_005249408 XP_005249465 XM_005249409 XP_005249466 NM_001168357 NP_001161829 NM_005084 NP_005075
|
| Function |
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
|
| Subcellular Location |
Secreted, extracellular space.
|
| Tissue Specificity |
Plasma.
|
| Top Pathways |
Ether lipid metabolism
|
![Western Blot: PLA2G7 Overexpression Lysate (Adult Normal) [NBL1-14477] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PLA2G7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/9901_PLA2G7%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-14477-img0002.jpg)