Gene Symbol | PLA2G7 |
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Entrez Gene | 7941 |
Alt Symbol | LDL-PLA2, LP-PLA2, PAFAD, PAFAH |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
Other Description | 1-alkyl-2-acetylglycerophosphocholine esterase|2-acetyl-1-alkylglycerophosphocholine esterase|LDL-PLA(2)|LDL-associated phospholipase A2|PAF 2-acylhydrolase|PAF acetylhydrolase|gVIIA-PLA2|group-VIIA phospholipase A2|lipoprotein-associated phospholipase A2|platelet-activating factor acetylhydrolase |
Swissprots | Q15692 Q5VTT1 A5HTT5 Q13093 Q8IVA2 |
Accessions | ABQ01234 EAX04301 EAX04302 Q13093 AK290381 BAF83070 AK294471 BAG57699 AK297066 BAG59587 BC025674 BC038452 AAH38452 BP326231 HQ448549 ADQ33028 U20157 AAC50126 U24577 AAB04170 XM_005249408 XP_005249465 XM_005249409 XP_005249466 NM_001168357 NP_001161829 NM_005084 NP_005075 |
Function | Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Plasma. |
Top Pathways | Ether lipid metabolism |
Active human PAFAH full length protein - ab82130 from Abcam
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Human PAFAH full length protein - ab166875 from Abcam
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Human PAFAH full length protein - ab152087 from Abcam
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Human PAFAH full length protein - ab87477 from Abcam
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Human PAFAH protein fragment - ab187612 from Abcam
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LP-PLA2 / PLA2G7 Antibody Blocking Peptide - LS-E10337 from LifeSpan Bioscience
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LP-PLA2 / PLA2G7 Antibody Blocking Peptide - LS-E28048 from LifeSpan Bioscience
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PLA2G7/PAF-AH/Lp-PLA2 Recombinant Protein - H00007941-P01 from Novus Biologicals
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PLA2G7-Antibody-Center-Blocking-Peptide - BP9819c from Abgent, a WuXi AppTec company
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PLA2G7 recombinant protein - GTX53846 from GeneTex
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Recombinant Human PLA2G7/PAF-AH/Lp-PLA2, CF - 5106-PL-010 from R&D Systems
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Recombinant human Platelet-activating factor acetylhydrolase (OPCA00790) - OPCA00790 from Aviva Systems Biology
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PLA2G7 Protein (OPPA01811) - OPPA01811 from Aviva Systems Biology
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Lipoprotein-Associated Phospholipase A2 (Western Blot Control) Protein (OPRB00280) - OPRB00280 from Aviva Systems Biology
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Lipoprotein-Associated Phospholipase A2 Protein (OPRB00281) - OPRB00281 from Aviva Systems Biology
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Lipoprotein-Associated Phospholipase A2 Protein (OPRB00282) - OPRB00282 from Aviva Systems Biology
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Human PLA2G7 protein - orb245404 from Biorbyt
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Human PLA2G7 protein - orb246560 from Biorbyt
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Human PLA2G7 protein - orb246854 from Biorbyt
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Human PLA2G7, HEK protein - orb191399 from Biorbyt
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Human LpPLA2 protein - orb49591 from Biorbyt
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Human PLA2G7 His tag protein - orb84168 from Biorbyt
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Human Secreted Phospholipase A2-VII protein - orb90229 from Biorbyt
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PAFAH protein - 30-1367 from Fitzgerald
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PAFAH protein - 30R-AP045 from Fitzgerald
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