| Gene Symbol | GARS |
|---|---|
| Entrez Gene | 2617 |
| Alt Symbol | CMT2D, DSMAV, GlyRS, HMN5, SMAD1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | glycyl-tRNA synthetase |
| Other Description | AP-4-A synthetase|Charcot-Marie-Tooth neuropathy 2D|Charcot-Marie-Tooth neuropathy, neuronal type, D|diadenosine tetraphosphate synthetase|glycine tRNA ligase|glycine--tRNA ligase |
| Swissprots | Q969Y1 B4DIA0 P41250 B3KQA2 |
| Accessions | AAC71652 AAS00367 EAL24449 EAW93960 EAW93961 P41250 AA772440 AK074524 BAG51964 AK295490 BAG58412 AK310351 BC000065 BC007722 AAH07722 BC007755 AAH07755 D30658 BAA06338 DQ892773 ABM83699 DQ896021 ABM87020 U09510 AAA86443 U09587 AAA57001 XM_006715686 XP_006715749 NM_002047 NP_002038 |
| Function | Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. {ECO:0000269|PubMed:19710017}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9524218}. Mitochondrion {ECO:0000269|PubMed:9524218}. |
| Tissue Specificity | Widely expressed, including brain and spinal cord. {ECO:0000269|PubMed:12690580}. |
| Top Pathways | Aminoacyl-tRNA biosynthesis |
Human GARS / Glycyl tRNA Synthetase ELISA Kit (Sandwich ELISA) - LS-F8074 from LifeSpan Bioscience
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Phospho-Smad1 (S463/S465)/Smad5 (S463/S465) Cell-Based ELISA - KCB7660 from R&D Systems
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Human GARS ELISA Kit - abx151627 from Abbexa
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Anti glycyl-tRNA synthetase (GARS) antibody, Human, ELISA kit - CSB-EQ027702HU from ARP American Research Products
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Glycyl tRNA Synthetase, GARS, Human, ELISA Kit - E-EL-H1043 from ARP American Research Products
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Glycyl tRNA Synthetase (GARS), Human, ELISA Kit - SEC996Hu from ARP American Research Products
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Glycyl-tRNA synthetase (GARS), Human, ELISA Kit - CSB-EL009262HU from ARP American Research Products
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Mothers against decapentaplegic homolog 1, SMAD1, Human, ELISA Kit - E0647h from ARP American Research Products
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Glycyl tRNA Synthetase, GARS, Rabbit, ELISA Kit - E-EL-RB1073 from ARP American Research Products
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Glycyl tRNA Synthetase, GARS, Chicken, ELISA Kit - E-EL-Ch1631 from ARP American Research Products
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Glycyl tRNA Synthetase, GARS, Porcine, ELISA Kit - E-EL-P1720 from ARP American Research Products
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Glycyl tRNA Synthetase, GARS, Sheep, ELISA Kit - E-EL-S0784 from ARP American Research Products
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Glycyl tRNA Synthetase, GARS, Monkey, ELISA Kit - E-EL-MK0373 from ARP American Research Products
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GARS (Human) IP-WB Antibody Pair - H00002617-PW1 from Acris Antibodies
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Human Smad1 ELISA Kit - HS0276 from NeoScientific
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Human EJ/GlyRS ELISA Kit - HE0142 from NeoScientific
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Guinea Pig EJ/GlyRS ELISA Kit - GE0142 from NeoScientific
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Bovine EJ/GlyRS ELISA Kit - BE0142 from NeoScientific
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Canine EJ/GlyRS ELISA Kit - CE0142 from NeoScientific
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Porcine EJ/GlyRS ELISA Kit - PE0142 from NeoScientific
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Goat EJ/GlyRS ELISA Kit - GTE0142 from NeoScientific
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Rabbit EJ/GlyRS ELISA Kit - RTE0142 from NeoScientific
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Anserine EJ/GlyRS ELISA Kit - AE0142 from NeoScientific
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Anserine Smad1 ELISA Kit - AS0276 from NeoScientific
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Human Smad1/MADH1(Mothers Against Decapentaplegic Homolog 1) ELISA Kit - E-EL-H0932 from Elabscience
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