| Gene Symbol | GARS |
|---|---|
| Entrez Gene | 2617 |
| Alt Symbol | CMT2D, DSMAV, GlyRS, HMN5, SMAD1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | glycyl-tRNA synthetase |
| Other Description | AP-4-A synthetase|Charcot-Marie-Tooth neuropathy 2D|Charcot-Marie-Tooth neuropathy, neuronal type, D|diadenosine tetraphosphate synthetase|glycine tRNA ligase|glycine--tRNA ligase |
| Swissprots | Q969Y1 B4DIA0 P41250 B3KQA2 |
| Accessions | AAC71652 AAS00367 EAL24449 EAW93960 EAW93961 P41250 AA772440 AK074524 BAG51964 AK295490 BAG58412 AK310351 BC000065 BC007722 AAH07722 BC007755 AAH07755 D30658 BAA06338 DQ892773 ABM83699 DQ896021 ABM87020 U09510 AAA86443 U09587 AAA57001 XM_006715686 XP_006715749 NM_002047 NP_002038 |
| Function | Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. {ECO:0000269|PubMed:19710017}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9524218}. Mitochondrion {ECO:0000269|PubMed:9524218}. |
| Tissue Specificity | Widely expressed, including brain and spinal cord. {ECO:0000269|PubMed:12690580}. |
| Top Pathways | Aminoacyl-tRNA biosynthesis |
GARS - MBS1278720 from MyBioSource
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Human GARS cDNA clone(NM_002047.2) - CDFH007369 from Creative Biomart
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Human GARS cDNA clone(NM_002047.2) - CDFH007370 from Creative Biomart
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Human GARS ORF Clone(NM_002047.2) - CDCR282245 from Creative Biomart
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Human GARS ORF Clone(NM_002047.2) - CDCR282246 from Creative Biomart
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Human GARS ORF Clone(NM_002047.2) - CDCR282247 from Creative Biomart
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Human GARS ORF Clone(NM_002047.2) - CDCL164343 from Creative Biomart
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Human GARS ORF Clone(NM_002047.2) - CDCL164344 from Creative Biomart
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Human GARS ORF Clone(NM_002047.2) - CDCL164345 from Creative Biomart
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Human GARS ORF clone - CDCL110651 from Creative Biomart
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Human GARS ORF clone - CDCL110652 from Creative Biomart
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Mouse GARS ORF clone - CDCL110653 from Creative Biomart
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Mouse GARS ORF clone - CDCL110654 from Creative Biomart
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Human GARS ORF clone - CDCL110655 from Creative Biomart
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Human GARS ORF clone - CDCL110656 from Creative Biomart
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Human GARS ORF clone - CDCL110657 from Creative Biomart
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Human GARS ORF clone - CDCL110658 from Creative Biomart
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Human Smad1 ORF clone(NM_001003688.1) - CDCL186231 from Creative Biomart |
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Human GARS ORF clone (NM_002047.2) - CDCL110651 from Creative biogene
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Human GARS ORF Clone (BC000065) - CDCS410579 from Creative biogene
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Human GARS cDNA Clone(NM_002047.2) - CDFH007369 from Creative biogene
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Human GARS cDNA Clone(NM_002047.2) - CDFH007370 from Creative biogene
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