GARS

Gene Symbol	GARS
Entrez Gene	2617
Alt Symbol	CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Species	Human
Gene Type	protein-coding
Description	glycyl-tRNA synthetase
Other Description	AP-4-A synthetase|Charcot-Marie-Tooth neuropathy 2D|Charcot-Marie-Tooth neuropathy, neuronal type, D|diadenosine tetraphosphate synthetase|glycine tRNA ligase|glycine--tRNA ligase
Swissprots	Q969Y1 B4DIA0 P41250 B3KQA2
Accessions	AAC71652 AAS00367 EAL24449 EAW93960 EAW93961 P41250 AA772440 AK074524 BAG51964 AK295490 BAG58412 AK310351 BC000065 BC007722 AAH07722 BC007755 AAH07755 D30658 BAA06338 DQ892773 ABM83699 DQ896021 ABM87020 U09510 AAA86443 U09587 AAA57001 XM_006715686 XP_006715749 NM_002047 NP_002038
Function	Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. {ECO:0000269|PubMed:19710017}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9524218}. Mitochondrion {ECO:0000269|PubMed:9524218}.
Tissue Specificity	Widely expressed, including brain and spinal cord. {ECO:0000269|PubMed:12690580}.
Top Pathways	Aminoacyl-tRNA biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GARS full length protein - ab185611 from Abcam Category Protein Source E. coli Species Human

Human GARS protein fragment - ab132498 from Abcam Category Protein Source Wheat germ Species Human

Human GARS protein fragment - ab180328 from Abcam Category Protein Source E. coli Species Human

GARS / Glycyl tRNA Synthetase Antibody Blocking Peptide - LS-E21500 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GARS / Glycyl tRNA Synthetase Antibody Blocking Peptide - LS-E9388 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMAD1 Antibody Blocking Peptide - LS-E11182 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Smad1 Protein - H00004086-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Smad1 Protein - H00004086-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GARS Protein - H00002617-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GARS-Antibody-C-term-Blocking-Peptide - BP7952b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human GARS protein - orb168380 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

GARS Blocking Peptide - 33R-3949 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GARS protein (His tag) - 80R-3889 from Fitzgerald Category Protein Prices $375.00 Sizes 50 µg Source E.coli

GARS protein (His tag) - 80-1374 from Fitzgerald Category Protein Prices $95.00, $495.00 Sizes 100 µg, 1 mg Source E.coli

SMAD1 Blocking Peptide - 33R-10771 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

Smad1 Blocking Peptide - 33R-10495 from Fitzgerald Category Peptide Prices $295.00 Sizes 50 µg

SMAD1 (phospho-Ser187) Blocking Peptide - abx062898 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Sheep

SMAD1 Blocking Peptide - abx062899 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Zebrafish

Glycyl-tRNA synthetase (43-289, His-tag) - AR51576PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

Glycyl-tRNA synthetase (43-289, His-tag) - AR51576PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

Glycyl-tRNA synthetase - H00002617-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Glycyl-tRNA synthetase - H00002617-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Glycyl-tRNA synthetase - P5933 from Acris Antibodies Category Protein Prices $750.00 Sizes 50 µg Species Human

GARS, 43-289aa, Human, His tag, E.coli - 01-P2756 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

GARS fusion protein - Ag8322 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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