GARS

Gene Symbol GARS
Entrez Gene 2617
Alt Symbol CMT2D, DSMAV, GlyRS, HMN5, SMAD1
Species Human
Gene Type protein-coding
Description glycyl-tRNA synthetase
Other Description AP-4-A synthetase|Charcot-Marie-Tooth neuropathy 2D|Charcot-Marie-Tooth neuropathy, neuronal type, D|diadenosine tetraphosphate synthetase|glycine tRNA ligase|glycine--tRNA ligase
Swissprots Q969Y1 B4DIA0 P41250 B3KQA2
Accessions AAC71652 AAS00367 EAL24449 EAW93960 EAW93961 P41250 AA772440 AK074524 BAG51964 AK295490 BAG58412 AK310351 BC000065 BC007722 AAH07722 BC007755 AAH07755 D30658 BAA06338 DQ892773 ABM83699 DQ896021 ABM87020 U09510 AAA86443 U09587 AAA57001 XM_006715686 XP_006715749 NM_002047 NP_002038
Function Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. {ECO:0000269|PubMed:19710017}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:9524218}. Mitochondrion {ECO:0000269|PubMed:9524218}.
Tissue Specificity Widely expressed, including brain and spinal cord. {ECO:0000269|PubMed:12690580}.
Top Pathways Aminoacyl-tRNA biosynthesis

GlyRS CRISPR/Cas9 KO Plasmid (h) - sc-404105 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS HDR Plasmid (h) - sc-404105-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS Double Nickase Plasmid (h) - sc-404105-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS Double Nickase Plasmid (h2) - sc-404105-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS CRISPR Activation Plasmid (h) - sc-404105-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS CRISPR Activation Plasmid (h2) - sc-404105-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS Lentiviral Activation Particles (h) - sc-404105-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS Lentiviral Activation Particles (h2) - sc-404105-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GlyRS siRNA (h) - sc-75153 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GlyRS shRNA Plasmid (h) - sc-75153-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GlyRS shRNA (h) Lentiviral Particles - sc-75153-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Smad1 RNAi - H00004086-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU052091 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9134 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9134 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00468 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00468

GARS siRNA (Human) - CRH1733 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GARS - MBS8212433 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GARS (NM_002047.2) - SHH299369 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GARS(NM_002047.2) - SHH077519 from Creative biogene

Category siRNA
Species Reactivities Human

GARS shRNA Plasmid (Human) - CHH1733 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GARS miRNA 3'UTR clone - MiUTR1H-03956 from Creative biogene

Species Reactivities Human
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