Cyr61

Gene Symbol Cyr61
Entrez Gene 16007
Alt Symbol AI325051, CCN1, Igfbp10
Species Mouse
Gene Type protein-coding
Description cysteine rich protein 61
Other Description 3CH61|CCN family member 1|IBP-10|IGF-binding protein 10|IGFBP-10|cysteine-rich angiogenic inducer 61|insulin-like growth factor binding protein 10|insulin-like growth factor-binding protein 10|intermediate early|protein CYR61
Swissprots P18406
Accessions CAA40109 CAS92740 CBX51737 EDL11998 P18406 AK156723 BAE33819 AK159452 BAE35095 BC003205 BC066019 AAH66019 M32490 AAA37512 NM_010516 NP_034646
Function Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CYR61-mediated gene regulation is dependent on heparin-binding (By similarity). Down- regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 (By similarity). {ECO:0000250}.
Subcellular Location Secreted.
Tissue Specificity Low in kidney, adrenal gland, testes, brain, and ovary, moderate in heart, uterus, and skeletal muscle, highest in lung.

Cyr61 CRISPR/Cas9 KO Plasmid (m) - sc-421062 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 HDR Plasmid (m) - sc-421062-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 Double Nickase Plasmid (m) - sc-421062-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 Double Nickase Plasmid (m2) - sc-421062-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 CRISPR Activation Plasmid (m) - sc-421062-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 CRISPR Activation Plasmid (m2) - sc-421062-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 Lentiviral Activation Particles (m) - sc-421062-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 Lentiviral Activation Particles (m2) - sc-421062-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Cyr61 siRNA (m) - sc-39332 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Cyr61 shRNA Plasmid (m) - sc-39332-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Cyr61 shRNA (m) Lentiviral Particles - sc-39332-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU026621 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN29597 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29597 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CYR61 siRNA (Mouse) - CRM2017 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CYR61 - MBS8214644 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

Mouse CYR61 siRNA - orb281493 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CYR61 shRNA Plasmid (Mouse) - CHM2017 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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