| Gene Symbol |
FBF1
|
| Entrez Gene |
85302
|
| Alt Symbol |
Alb, FBF-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Fas (TNFRSF6) binding factor 1
|
| Other Description |
Fas binding protein 1|albatross|fas-binding factor 1|protein albatross
|
| Swissprots |
Q8TES7 Q96JG4 Q96IF6 Q96MA8 B5MEM5
|
| Accessions |
EAW89342 Q8TES7 AB354594 BAG71501 AK057261 BAB71400 AK074045 BAB84871 BC007570 AAH07570 BC012332 AAH12332 BC023549 AAH23549 NM_001080542 NP_001074011
|
| Function |
Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis. {ECO:0000269|PubMed:18838552, ECO:0000269|PubMed:23348840}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell junction. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells.
|
| Tissue Specificity |
Present in various epithelial cells (at protein level).
|