Gene Symbol | FBF1 |
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Entrez Gene | 85302 |
Alt Symbol | Alb, FBF-1 |
Species | Human |
Gene Type | protein-coding |
Description | Fas (TNFRSF6) binding factor 1 |
Other Description | Fas binding protein 1|albatross|fas-binding factor 1|protein albatross |
Swissprots | Q8TES7 Q96JG4 Q96IF6 Q96MA8 B5MEM5 |
Accessions | EAW89342 Q8TES7 AB354594 BAG71501 AK057261 BAB71400 AK074045 BAB84871 BC007570 AAH07570 BC012332 AAH12332 BC023549 AAH23549 NM_001080542 NP_001074011 |
Function | Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis. {ECO:0000269|PubMed:18838552, ECO:0000269|PubMed:23348840}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell junction. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells. |
Tissue Specificity | Present in various epithelial cells (at protein level). |
FBF1 CRISPR/Cas9 KO Plasmid (h) - sc-407987 from Santa Cruz Biotechnology
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FBF1 HDR Plasmid (h) - sc-407987-HDR from Santa Cruz Biotechnology
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FBF1 Double Nickase Plasmid (h) - sc-407987-NIC from Santa Cruz Biotechnology
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FBF1 Double Nickase Plasmid (h2) - sc-407987-NIC-2 from Santa Cruz Biotechnology
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FBF1 CRISPR Activation Plasmid (h) - sc-407987-ACT from Santa Cruz Biotechnology
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FBF1 CRISPR Activation Plasmid (h2) - sc-407987-ACT-2 from Santa Cruz Biotechnology
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FBF1 Lentiviral Activation Particles (h) - sc-407987-LAC from Santa Cruz Biotechnology
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FBF1 Lentiviral Activation Particles (h2) - sc-407987-LAC-2 from Santa Cruz Biotechnology
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FBF1 siRNA (h) - sc-94101 from Santa Cruz Biotechnology
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FBF1 shRNA Plasmid (h) - sc-94101-SH from Santa Cruz Biotechnology
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FBF1 shRNA (h) Lentiviral Particles - sc-94101-V from Santa Cruz Biotechnology
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Human Serum Albumin RNAi - H00000213-R01 from Novus Biologicals
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MISSION® esiRNA - EHU096321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8500 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8500 from Sigma-Aldrich
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FBF1 siRNA (Human) - CRJ3774 from Cohesion Biosciences
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FBF1 - MBS8214867 from MyBioSource
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shRNA set against Human FBF1 (NM_001080542.1) - SHH292641 from Creative biogene
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shRNA set against Human FBF1(NM_001080542.1) - SHH050033 from Creative biogene
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Human FBF1 siRNA - orb274275 from Biorbyt
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FBF1 shRNA Plasmid (Human) - CHJ3774 from Cohesion Biosciences
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FBF1 miRNA 3'UTR clone - MiUTR1H-03525 from Creative biogene
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