CBY1

Gene Symbol CBY1
Entrez Gene 25776
Alt Symbol C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1
Species Human
Gene Type protein-coding
Description chibby homolog 1 (Drosophila)
Other Description ARPP-binding protein|PKD2 interactor, Golgi and endoplasmic reticulum-associated 1|PKD2 interactor, golgi and endoplasmic reticulum associated 1|chibby CTNNB1-mediated transcription inhibitor|coiled-coil protein PIGEA-14|cytosolic leucine-rich protein|polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa|protein chibby homolog 1
Swissprots Q9UIK9 Q9Y3M2 B2R4S2 Q66GT6
Accessions DAA05582 EAW60254 EAW60255 EAW60256 Q9Y3M2 AB015347 BAA88119 AB111855 BAC78839 AF331041 AAL56062 AK307265 AK311928 BAG34869 AL050345 CAB43547 AL136686 CAB66621 AU099418 BC008839 BC016139 AAH16139 CD626926 CD702742 CR456410 CAG30296 HQ258005 ADR82759 NM_001002880 NP_001002880 NM_015373 NP_056188
Function Inhibits the Wnt/Wingless pathway by binding to beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. {ECO:0000269|PubMed:12712206, ECO:0000269|PubMed:15194699}.
Subcellular Location Nucleus speckle. Golgi apparatus, trans- Golgi network. Note=Nuclear, in a punctate manner. Also found in the trans-Golgi.
Tissue Specificity Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors. {ECO:0000269|PubMed:12712206}.

Chibby CRISPR/Cas9 KO Plasmid (h) - sc-405662 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby HDR Plasmid (h) - sc-405662-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby Double Nickase Plasmid (h) - sc-405662-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby Double Nickase Plasmid (h2) - sc-405662-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby CRISPR Activation Plasmid (h) - sc-405662-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby CRISPR Activation Plasmid (h2) - sc-405662-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby Lentiviral Activation Particles (h) - sc-405662-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby Lentiviral Activation Particles (h2) - sc-405662-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chibby siRNA (h) - sc-72890 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Chibby shRNA Plasmid (h) - sc-72890-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Chibby shRNA (h) Lentiviral Particles - sc-72890-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PGEA1 RNAi - H00025776-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU048501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5433 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5433 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05043 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05043

CBY1 siRNA (Human) - CRH8488 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PGEA1 RNAi - H00025776-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CBY1 - MBS8217126 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CBY1 (NM_015373.3) - SHH255581 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CBY1(NM_001002880.1) - SHG145675 from Creative biogene

Category siRNA
Species Reactivities Human

Human CBY1 siRNA - orb268990 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBY1 shRNA Plasmid (Human) - CHH8488 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

Cby1 miRNA 3'UTR clone - MiUTR1H-01713 from Creative biogene

Species Reactivities Human

Cby1 miRNA 3'UTR clone - MiUTR3H-09449 from Creative biogene

Species Reactivities Human
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