Gene Symbol | TCTN2 |
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Entrez Gene | 79867 |
Alt Symbol | C12orf38, MKS8, TECT2 |
Species | Human |
Gene Type | protein-coding |
Description | tectonic family member 2 |
Other Description | tectonic-2 |
Swissprots | Q9H966 B3KPW5 Q96GX1 A8K7Y8 |
Accessions | EAW98430 Q96GX1 AK023037 BAB14370 AK056924 BAG51827 AK292153 BAF84842 BC009112 AAH09112 BM997327 BQ774678 DQ278870 ABB90562 XM_005253623 XP_005253680 XM_006719605 XP_006719668 XM_011538748 XP_011537050 NM_001143850 NP_001137322 NM_024809 NP_079085 |
Function | Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}. |
tectonic family member 2, ELISA Kit - MBS9327096 from MyBioSource
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Human TCTN2 ELISA Kit - E037640 from Biobool
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anti-TCTN2 antibody - ARG54662 from Arigo Biolaboratories
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