| Gene Symbol |
TCTN2
|
| Entrez Gene |
79867
|
| Alt Symbol |
C12orf38, MKS8, TECT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tectonic family member 2
|
| Other Description |
tectonic-2
|
| Swissprots |
Q9H966 B3KPW5 Q96GX1 A8K7Y8
|
| Accessions |
EAW98430 Q96GX1 AK023037 BAB14370 AK056924 BAG51827 AK292153 BAF84842 BC009112 AAH09112 BM997327 BQ774678 DQ278870 ABB90562 XM_005253623 XP_005253680 XM_006719605 XP_006719668 XM_011538748 XP_011537050 NM_001143850 NP_001137322 NM_024809 NP_079085
|
| Function |
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}.
|
![Western Blot: TCTN2 Overexpression Lysate (Adult Normal) [NBL1-16795] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TCTN2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9345_TCTN2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16795-img0002.jpg)