Gene Symbol | TCTN2 |
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Entrez Gene | 79867 |
Alt Symbol | C12orf38, MKS8, TECT2 |
Species | Human |
Gene Type | protein-coding |
Description | tectonic family member 2 |
Other Description | tectonic-2 |
Swissprots | Q9H966 B3KPW5 Q96GX1 A8K7Y8 |
Accessions | EAW98430 Q96GX1 AK023037 BAB14370 AK056924 BAG51827 AK292153 BAF84842 BC009112 AAH09112 BM997327 BQ774678 DQ278870 ABB90562 XM_005253623 XP_005253680 XM_006719605 XP_006719668 XM_011538748 XP_011537050 NM_001143850 NP_001137322 NM_024809 NP_079085 |
Function | Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}. |
Tect2 CRISPR/Cas9 KO Plasmid (h) - sc-413277 from Santa Cruz Biotechnology
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Tect2 HDR Plasmid (h) - sc-413277-HDR from Santa Cruz Biotechnology
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Tect2 Double Nickase Plasmid (h) - sc-413277-NIC from Santa Cruz Biotechnology
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Tect2 Double Nickase Plasmid (h2) - sc-413277-NIC-2 from Santa Cruz Biotechnology
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Tect2 CRISPR Activation Plasmid (h) - sc-413277-ACT from Santa Cruz Biotechnology
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Tect2 CRISPR Activation Plasmid (h2) - sc-413277-ACT-2 from Santa Cruz Biotechnology
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Tect2 Lentiviral Activation Particles (h) - sc-413277-LAC from Santa Cruz Biotechnology
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Tect2 Lentiviral Activation Particles (h2) - sc-413277-LAC-2 from Santa Cruz Biotechnology
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Tect2 siRNA (h) - sc-96207 from Santa Cruz Biotechnology
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Tect2 shRNA Plasmid (h) - sc-96207-SH from Santa Cruz Biotechnology
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Tect2 shRNA (h) Lentiviral Particles - sc-96207-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU050711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21176 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21176 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05819 from Sigma-Aldrich
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TCTN2 siRNA (Human) - CRJ2625 from Cohesion Biosciences
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TCTN2 - MBS8232317 from MyBioSource
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shRNA set against Human TCTN2 (NM_024809.4) - SHH425224 from Creative biogene
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TCTN2 shRNA Plasmid (Human) - CHJ2625 from Cohesion Biosciences
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TCTN2 miRNA 3'UTR clone - MiUTR3H-13048 from Creative biogene
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TCTN2 miRNA 3'UTR clone - MiUTR3H-13049 from Creative biogene
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