Gene Symbol | GALR2 |
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Entrez Gene | 8811 |
Alt Symbol | GAL2-R, GALNR2, GALR-2 |
Species | Human |
Gene Type | protein-coding |
Description | galanin receptor 2 |
Other Description | galanin receptor type 2 |
Swissprots | A5JUU4 Q32MN8 O43603 |
Accessions | AAC18118 AAC36587 EAW89364 O43603 AF040630 AAC39634 AF080586 AAD08671 BC069130 AAH69130 BC074914 AAH74914 BC074915 AAH74915 BC109051 AAI09052 BC109052 AAI09053 BU631750 EF577401 ABQ52421 XM_011525427 XP_011523729 NM_003857 NP_003848 |
Function | Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)). {ECO:0000269|PubMed:24517231}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine. |
Top Pathways | Neuroactive ligand-receptor interaction |
GALR2 (K-20) - sc-16219 from Santa Cruz Biotechnology
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GALR2 (H-90) - sc-30023 from Santa Cruz Biotechnology
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GALR2 (L-20) - sc-16217 from Santa Cruz Biotechnology
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Anti-GALR2 antibody - ab203072 from Abcam
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Anti-GALR2 antibody - ab59029 from Abcam
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Anti-GALR2 antibody - ab96499 from Abcam
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Anti-GALR2 antibody - ab136234 from Abcam
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Anti-GALR2 antibody - ab96702 from Abcam
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Anti-GALR2 / Galanin Receptor 2 Antibody IHC-plus⢠- LS-B4081 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (Transmembrane Domain) IHC-plus⢠- LS-A4156 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (aa189-238) - LS-C291983 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (C-Terminus) - LS-C145625 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (aa201-250) - LS-C120667 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (aa243-336) - LS-C185368 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (aa128-141) - LS-C54898 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (Ile238) - LS-C177201 from LifeSpan Bioscience
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Anti-GALR2 / Galanin Receptor 2 Antibody (C-Terminus) IHC-plus⢠- LS-A4155 from LifeSpan Bioscience
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Galanin R2/GALR2 Antibody (616520) - MAB6544 from Novus Biologicals
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Galanin R2/GALR2 Antibody - NBP1-00842 from Novus Biologicals
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Galanin R2/GALR2 Antibody - NBP1-91921 from Novus Biologicals
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Galanin R2/GALR2 Antibody - NB100-57081 from Novus Biologicals
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Galanin R2/GALR2 Antibody - NLS4156 from Novus Biologicals
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Galanin R2/GALR2 Antibody - NLS4154 from Novus Biologicals
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GALR2 Polyclonal Antibody - bs-11527R from Bioss
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GALR2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11527R-A350 from Bioss
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