| Gene Symbol | GALR2 |
|---|---|
| Entrez Gene | 8811 |
| Alt Symbol | GAL2-R, GALNR2, GALR-2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | galanin receptor 2 |
| Other Description | galanin receptor type 2 |
| Swissprots | A5JUU4 Q32MN8 O43603 |
| Accessions | AAC18118 AAC36587 EAW89364 O43603 AF040630 AAC39634 AF080586 AAD08671 BC069130 AAH69130 BC074914 AAH74914 BC074915 AAH74915 BC109051 AAI09052 BC109052 AAI09053 BU631750 EF577401 ABQ52421 XM_011525427 XP_011523729 NM_003857 NP_003848 |
| Function | Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)). {ECO:0000269|PubMed:24517231}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine. |
| Top Pathways | Neuroactive ligand-receptor interaction |
Galanin Receptor2, GALR2, Rat, ELISA Kit - E-EL-R1407 from ARP American Research Products
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galanin receptor 2, ELISA Kit - MBS9342397 from MyBioSource
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Galanin Receptor 2 (GALR2), ELISA Kit - MBS9311996 from MyBioSource
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GALR2, ELISA Kit - MBS2504824 from MyBioSource
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Human GALR2 ELISA Kit - E015960 from Biobool
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anti-GALR2 antibody - ARG64131 from Arigo Biolaboratories
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Rat GALR2 / Galanin Receptor 2 ELISA Kit (Sandwich ELISA) - LS-F38764 from LifeSpan Bioscience
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