Gene Symbol | GALR2 |
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Entrez Gene | 8811 |
Alt Symbol | GAL2-R, GALNR2, GALR-2 |
Species | Human |
Gene Type | protein-coding |
Description | galanin receptor 2 |
Other Description | galanin receptor type 2 |
Swissprots | A5JUU4 Q32MN8 O43603 |
Accessions | AAC18118 AAC36587 EAW89364 O43603 AF040630 AAC39634 AF080586 AAD08671 BC069130 AAH69130 BC074914 AAH74914 BC074915 AAH74915 BC109051 AAI09052 BC109052 AAI09053 BU631750 EF577401 ABQ52421 XM_011525427 XP_011523729 NM_003857 NP_003848 |
Function | Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)). {ECO:0000269|PubMed:24517231}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine. |
Top Pathways | Neuroactive ligand-receptor interaction |
GALR2 / Galanin Receptor 2 Blocking Peptide - LS-E28902 from LifeSpan Bioscience
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GALR2 / Galanin Receptor 2 Blocking Peptide - LS-E28903 from LifeSpan Bioscience
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GALR2 / Galanin Receptor 2 Antibody Blocking Peptide - LS-E28904 from LifeSpan Bioscience
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GALR2 / Galanin Receptor 2 Antibody Blocking Peptide - LS-E22447 from LifeSpan Bioscience
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GALR2 / Galanin Receptor 2 Antibody Blocking Peptide - LS-E26233 from LifeSpan Bioscience
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GALR2 blocking peptide - GTX89151-PEP from GeneTex
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GALR2 Blocking Peptide - 33R-10391 from Fitzgerald
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Galanin Receptor 2 Peptide - AC21-1065-P from Abcore
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GALR2 Peptide - 45-654P from ProSci
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GALR2 fusion protein - Ag24162 from Proteintech Group
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GALR2 fusion protein - ag13220 from Proteintech Group
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ChemiSCREEN™ Human Recombinant GAL2 Galanin Receptor Calcium-Optimized Stable Cell Line - HTS186C from EMD Millipore
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ChemiSCREEN™ Membrane Preparation Recombinant Human GAL 2 Galanin Receptor - HTS186M from EMD Millipore
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GALR2 Blocking Peptide - CBP3362 from Cohesion Biosciences
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GALR2 (I238) Peptide - BS2797P from Bioworld Technology
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GALR2, Peptide - MBS426367 from MyBioSource
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Galanin R2/GALR2 Recombinant Protein Antigen - NBP1-91921PEP from Novus Biologicals
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GALR2 Blocking Peptide - abx162224 from Abbexa
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GALR2-Antibody-Center-Blocking-Peptide - BP9347c from Abgent, a WuXi AppTec company
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GALR2 Peptide, Human - M34GP06095H from Creative Peptides
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Galanin receptor type 2 (GALR2), Recombinant Protein - MBS7015453 from MyBioSource
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Galanin receptor type 2 (GALR2), Recombinant Protein - MBS1013630 from MyBioSource
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GALR2 Immunizing peptide - orb16184 from Biorbyt
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