Gene Symbol | GALR2 |
---|---|
Entrez Gene | 8811 |
Alt Symbol | GAL2-R, GALNR2, GALR-2 |
Species | Human |
Gene Type | protein-coding |
Description | galanin receptor 2 |
Other Description | galanin receptor type 2 |
Swissprots | A5JUU4 Q32MN8 O43603 |
Accessions | AAC18118 AAC36587 EAW89364 O43603 AF040630 AAC39634 AF080586 AAD08671 BC069130 AAH69130 BC074914 AAH74914 BC074915 AAH74915 BC109051 AAI09052 BC109052 AAI09053 BU631750 EF577401 ABQ52421 XM_011525427 XP_011523729 NM_003857 NP_003848 |
Function | Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)). {ECO:0000269|PubMed:24517231}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine. |
Top Pathways | Neuroactive ligand-receptor interaction |
GALR2 CRISPR/Cas9 KO Plasmid (h) - sc-403779 from Santa Cruz Biotechnology
|
||||||||
GALR2 HDR Plasmid (h) - sc-403779-HDR from Santa Cruz Biotechnology
|
||||||||
GALR2 Double Nickase Plasmid (h) - sc-403779-NIC from Santa Cruz Biotechnology
|
||||||||
GALR2 Double Nickase Plasmid (h2) - sc-403779-NIC-2 from Santa Cruz Biotechnology
|
||||||||
GALR2 CRISPR Activation Plasmid (h) - sc-403779-ACT from Santa Cruz Biotechnology
|
||||||||
GALR2 CRISPR Activation Plasmid (h2) - sc-403779-ACT-2 from Santa Cruz Biotechnology
|
||||||||
GALR2 Lentiviral Activation Particles (h) - sc-403779-LAC from Santa Cruz Biotechnology
|
||||||||
GALR2 Lentiviral Activation Particles (h2) - sc-403779-LAC-2 from Santa Cruz Biotechnology
|
||||||||
GALR2 siRNA (h) - sc-40008 from Santa Cruz Biotechnology
|
||||||||
GALR2 shRNA Plasmid (h) - sc-40008-SH from Santa Cruz Biotechnology
|
||||||||
GALR2 shRNA (h) Lentiviral Particles - sc-40008-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU138931 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN9121 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9121 from Sigma-Aldrich
|
||||||||
GALR2 siRNA (Human) - CRH5809 from Cohesion Biosciences
|
||||||||
Galanin R2/GALR2 RNAi - H00008811-R02 from Novus Biologicals
|
||||||||
GALR2 - MBS8208082 from MyBioSource
|
||||||||
shRNA set against Human GALR2 (NM_003857.2) - SHH299197 from Creative biogene
|
||||||||
shRNA set against Human GALR2(NM_003857.2) - SHH076817 from Creative biogene
|
||||||||
Human GALR2 siRNA - orb266311 from Biorbyt
|
||||||||
GALR2 shRNA Plasmid (Human) - CHH5809 from Cohesion Biosciences
|
||||||||
GALR2 miRNA 3'UTR clone - MiUTR1H-03945 from Creative biogene
|