Gene Symbol | VDR |
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Entrez Gene | 7421 |
Alt Symbol | NR1I1, PPP1R163 |
Species | Human |
Gene Type | protein-coding |
Description | vitamin D (1,25- dihydroxyvitamin D3) receptor |
Other Description | 1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1|protein phosphatase 1, regulatory subunit 163|vitamin D nuclear receptor variant 1|vitamin D3 receptor |
Swissprots | G3V1V9 P11473 B2R5Q1 Q5PSV3 |
Accessions | AAP88938 AAR10771 AAR19315 AAR19316 AAV85448 AGU41796 AGU41797 AGU41798 AGU41799 AGU41800 AGU41801 AGU41802 AGU41803 AGU41804 AGU41805 AGU41806 AGU41807 AGU41808 AGU41809 AGU41810 AGU41811 AID81985 BAA83389 CAC42552 EAW57959 EAW57960 EAW57961 EAW57962 EAW57963 P11473 AB307700 BAH02291 AF026260 AAB95155 AK024830 AK225844 AK299446 BAG61419 AK312267 BAG35198 BC033465 BC060832 AAH60832 BM685276 BM908433 BQ002808 BX355584 CF138099 DA721726 EU446665 ABZ92194 EU831779 ACE87297 EU831857 ACE86616 HQ692836 ADZ17347 J03258 AAA61273 M65208 AAA61274 X67482 CAA47824 XM_006719587 XP_006719650 XM_011538720 XP_011537022 NM_000376 NP_000367 NM_001017535 NP_001017535 NM_001017536 NP_001017536 |
Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. {ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:15728261, ECO:0000269|PubMed:16252006, ECO:0000269|PubMed:16913708}. |
Subcellular Location | Nucleus. |
Top Pathways | Mineral absorption, Endocrine and other factor-regulated calcium reabsorption, Tuberculosis |
Human VDR gene - orb92522 from Biorbyt
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Human-VDR-cDNA-Clone - DC08206 from Abgent, a WuXi AppTec company
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VDR - MBS1272702 from MyBioSource
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Human VDR cDNA clone(NM_000376.2) - CDFH021051 from Creative Biomart
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Human VDR cDNA clone(NM_001017535.1) - CDFH021052 from Creative Biomart
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Human VDR ORF clone(NM_000376.2) - CDCL186713 from Creative Biomart
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Human VDR ORF Clone(NM_000376.2) - CDCL180870 from Creative Biomart
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Human VDR ORF Clone(NM_000376.2) - CDCR336056 from Creative Biomart
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Human VDR ORF Clone(NM_000376.2) - CDCR336057 from Creative Biomart
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Human VDR ORF Clone(NM_000376.2) - CDCR336058 from Creative Biomart
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Human VDR ORF Clone(NM_001017535.1) - CDCR341881 from Creative Biomart
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Human VDR ORF Clone(NM_001017535.1) - CDCR341882 from Creative Biomart
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Human VDR ORF Clone(NM_001017535.1) - CDCR341883 from Creative Biomart
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human VDR ORF clone - CDCH099368 from Creative Biomart
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human VDR ORF clone - CDCH099369 from Creative Biomart
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human VDR ORF clone - CDCH099370 from Creative Biomart
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human VDR ORF clone - CDCH099371 from Creative Biomart
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Human VDR-NR111 Gene ORF cDNA clone in cloning vector - HG12025-G from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12025-NF from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12025-ACR from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, N-His tag - HG12025-NH from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12025-CF from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12025-NM from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12025-CM from Sino Biological
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Human VDR-NR111 Gene ORF cDNA clone expression plasmid, C-His tag - HG12025-CH from Sino Biological
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