| Gene Symbol |
Hspb1
|
| Entrez Gene |
24471
|
| Alt Symbol |
Hsp25, Hsp27
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
heat shock protein B1
|
| Other Description |
HSP 27|heat shock 27 kDa protein 1|heat shock 27kDa protein 1|heat shock protein beta-1
|
| Swissprots |
P42930 Q63922 Q9QWA8
|
| Accessions |
AAB29536 EDM13341 P42930 FM035762 FQ215417 FQ221491 FQ222013 FQ222462 M86389 AAA41353 NM_031970 NP_114176
|
| Function |
Involved in stress resistance and actin organization.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in a variety of tissues. High levels in lung, adrenal, xiphoid, adipose tissue, heart and striated and smooth muscle, lower levels in the CNS. Adult levels are much higher in the slow-twitch soleus muscle than in the fast-twitch rectus femoris and extensor digitorum muscles. {ECO:0000269|PubMed:8282729}.
|
| Top Pathways |
VEGF signaling pathway, MAPK signaling pathway, Amoebiasis, Epstein-Barr virus infection
|