| Gene Symbol | Hspb1 |
|---|---|
| Entrez Gene | 24471 |
| Alt Symbol | Hsp25, Hsp27 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | heat shock protein B1 |
| Other Description | HSP 27|heat shock 27 kDa protein 1|heat shock 27kDa protein 1|heat shock protein beta-1 |
| Swissprots | P42930 Q63922 Q9QWA8 |
| Accessions | AAB29536 EDM13341 P42930 FM035762 FQ215417 FQ221491 FQ222013 FQ222462 M86389 AAA41353 NM_031970 NP_114176 |
| Function | Involved in stress resistance and actin organization. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles (By similarity). {ECO:0000250}. |
| Tissue Specificity | Expressed in a variety of tissues. High levels in lung, adrenal, xiphoid, adipose tissue, heart and striated and smooth muscle, lower levels in the CNS. Adult levels are much higher in the slow-twitch soleus muscle than in the fast-twitch rectus femoris and extensor digitorum muscles. {ECO:0000269|PubMed:8282729}. |
| Top Pathways | VEGF signaling pathway, MAPK signaling pathway, Amoebiasis, Epstein-Barr virus infection |
Recombinant Heat Shock 27kDa Protein 1 (HSPB1) - RPA693Ra01 from Cloud-clone
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Recombinant Heat Shock Protein Beta 2 (HSPb2) - RPA871Ra01 from Cloud-clone
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Recombinant Rat Heat shock protein beta-1(Hspb1) - CSB-YP010833RA CSB-EP010833RA CSB-BP010833RA CSB-MP010833RA from Cusabio
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Recombinant Rat HSPB1 Protein - HSPB1-2950R from Creative Biomart
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Heat shock protein beta-1 (Hspb1), Recombinant Protein - MBS965712 from MyBioSource
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