Gene Symbol | DDX17 |
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Entrez Gene | 10521 |
Alt Symbol | P72, RH70 |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
Other Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17|DEAD box protein p72|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)|RNA-dependent helicase p72|probable ATP-dependent RNA helicase DDX17 |
Swissprots | Q69YT1 Q6ICD6 Q92841 B1AHM0 |
Accessions | EAW60241 EAW60242 EAW60243 EAW60244 EAW60245 EAW60246 EAW60247 EAW60248 Q92841 AA765457 AB209595 BAD92832 AF131750 AAD20033 AK024985 AK074224 AK303049 BAG64169 AL080113 AL713763 CAH10627 AU130891 BC000595 AAH00595 BC029553 BC045747 BI545691 BP353248 CB215934 CR456432 CAG30318 CU012992 CAK54423 CU013280 CAK54722 U59321 AAC50787 NM_001098504 NP_001091974 NM_006386 NP_006377 NM_001098505 NM_030881 |
Function | RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation. {ECO:0000269|PubMed:11250900, ECO:0000269|PubMed:15298701, ECO:0000269|PubMed:17011493, ECO:0000269|PubMed:17226766, ECO:0000269|PubMed:18334637, ECO:0000269|PubMed:19718048}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:22002106}. Nucleus, nucleolus {ECO:0000269|PubMed:22002106}. |
Tissue Specificity | Ubiquitous. |
Human DDX17 peptide - ab31640 from Abcam
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Human DDX17 protein fragment - ab112392 from Abcam
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Human DDX17 protein fragment - ab153094 from Abcam
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DDX17 Antibody Blocking Peptide - LS-E13030 from LifeSpan Bioscience
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DDX17 Antibody Blocking Peptide - LS-E10066 from LifeSpan Bioscience
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Recombinant Human DDX17 Protein - H00010521-Q01 from Novus Biologicals
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Recombinant Human DDX17 Protein - H00010521-P01 from Novus Biologicals
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DDX17-Antibody-N-term-Blocking-Peptide - BP9322a from Abgent, a WuXi AppTec company
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DDX17 Blocking Peptide - 33R-7171 from Fitzgerald
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DDX17 Blocking Peptide - 33R-9297 from Fitzgerald
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DDX17 - H00010521-P01-10 from Acris Antibodies
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DDX17 - H00010521-P01-25 from Acris Antibodies
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DDX17 - H00010521-Q01-10 from Acris Antibodies
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DDX17 - H00010521-Q01-25 from Acris Antibodies
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DDX17,P72 fusion protein - Ag13723 from Proteintech Group
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DDX17,P72 fusion protein - ag13777 from Proteintech Group
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Recombinant Human DDX17 - DDX17-28323TH from Creative Biomart
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Recombinant Human DDX17, GST-tagged - DDX17-85H from Creative Biomart
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Recombinant Human Probable ATP-dependent RNA helicase DDX17(DDX17) - CSB-YP846106HU CSB-EP846106HU CSB-BP846106HU CSB-MP846106HU from Cusabio
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DDX17 (transcript variant 1) - TP300599 from Acris Antibodies
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Probable ATP-dependent RNA helicase DDX17 (DDX17), Recombinant Protein - MBS1291635 from MyBioSource
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DDX17 Recombinant Protein Antigen - NBP2-38985PEP from Novus Biologicals
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DDX17 Peptide, Human - M34GP04137H from Creative Peptides
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